MIF-AS1 MIF antisense RNA 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: MIF-AS1provided by HGNC
Official Full Name: MIF antisense RNA 1provided by HGNC
Primary source: HGNC:HGNC:27669
See related: AllianceGenome:HGNC:27669
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: MIF-AS
Expression: Broad expression in kidney (RPKM 42.5), prostate (RPKM 24.4) and 21 other tissues See more
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Genomic context

Location:: 22q11.23

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	22	NC_000022.11 (23893710..23898930, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	22	NC_060946.1 (24338309..24343529, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	22	NC_000022.10 (24235897..24241117, complement)

Chromosome 22 - NC_000022.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Correlation of MIF-AS1 polymorphisms with the risk and prognosis of gastric cancer.
Title: Correlation of MIF-AS1 polymorphisms with the risk and prognosis of gastric cancer.
Study shows that long non-coding RNA MIF-AS1 is upregulated and associated with oxidative phosphorylation pathway in gastric cancer. Its tumor-promoting role in gastric cancer was mainly dependent on positive regulation of NDUFA4.
Title: Long non-coding RNA MIF-AS1 promotes gastric cancer cell proliferation and reduces apoptosis to upregulate NDUFA4.
the MIF-AS rs755622 polymorphism may have a crucial role in the development of nephrolithiasis.
Title: Association Between MIF-AS rs755622 and Nephrolithiasis Risk in a Chinese Population.
It is the first study, which shows that the allele A (rs34383331T > A) in ncRNA is significantly associated with increased risk to Plasmodium falciparum malaria.
Title: Variations in ncRNA gene LOC284889 and MIF-794CATT repeats are associated with malaria susceptibility in Indian populations.
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.