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    Ankrd68 ankyrin repeat domain 68 [ Mus musculus (house mouse) ]

    Gene ID: 70981, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Ankrd68provided by MGI
    Official Full Name
    ankyrin repeat domain 68provided by MGI
    Primary source
    MGI:MGI:1918231
    See related
    Ensembl:ENSMUSG00000026774 AllianceGenome:MGI:1918231
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fem1al; Potegl; 4931423N10Rik
    Summary
    Is expressed in genitourinary system. Orthologous to several human genes including POTEA (POTE ankyrin domain family member A (gene/pseudogene)); POTEB (POTE ankyrin domain family member B); and POTEB2 (POTE ankyrin domain family member B2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 1.9), cerebellum adult (RPKM 0.2) and 2 other tissues See more
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    Genomic context

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    See Ankrd68 in Genome Data Viewer
    Location:
    2 A3; 2 15.25 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (23094769..23157141)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (23204748..23267129)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3361 Neighboring gene YME1-like 1 (S. cerevisiae) Neighboring gene nucleophosmin 1 pseudogene Neighboring gene predicted gene 13422 Neighboring gene neurexophilin 2 Neighboring gene predicted gene, 34769 Neighboring gene STARR-seq mESC enhancer starr_03927 Neighboring gene STARR-seq mESC enhancer starr_03928 Neighboring gene STARR-seq mESC enhancer starr_03929 Neighboring gene STARR-seq mESC enhancer starr_03930 Neighboring gene STARR-seq mESC enhancer starr_03931 Neighboring gene speckle-type BTB/POZ protein-like Neighboring gene ubiquitin-conjugating enzyme E2D 3 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC70981
    Names
    POTE ankyrin domain family, member G like
    fem-1 homolog A like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027635.1 → NP_081911.1  uncharacterized protein LOC70981

      See identical proteins and their annotated locations for NP_081911.1

      Status: VALIDATED

      Source sequence(s)
      AK016475, AV274829
      Consensus CDS
      CCDS50517.1
      UniProtKB/TrEMBL
      Q9D4J9
      Related
      ENSMUSP00000028113.4, ENSMUST00000028113.10
      Conserved Domains (4) summary
      cd00204
      Location:91 → 216
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:102 → 192
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:67 → 116
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:132 → 160
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      23094769..23157141
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319257.3 → XP_017174746.1  uncharacterized protein LOC70981 isoform X1

      Conserved Domains (2) summary
      PHA02874
      Location:89 → 259
      PHA02874; ankyrin repeat protein; Provisional
      sd00045
      Location:132 → 160
      ANK; ANK repeat [structural motif]

    2. XM_011239180.4 → XP_011237482.1  uncharacterized protein LOC70981 isoform X2

      Conserved Domains (2) summary
      PHA02874
      Location:89 → 268
      PHA02874; ankyrin repeat protein; Provisional
      sd00045
      Location:132 → 160
      ANK; ANK repeat [structural motif]

    3. XM_006498328.5 → XP_006498391.1  uncharacterized protein LOC70981 isoform X3

      Conserved Domains (2) summary
      PHA02874
      Location:89 → 268
      PHA02874; ankyrin repeat protein; Provisional
      sd00045
      Location:132 → 160
      ANK; ANK repeat [structural motif]

    RNA

    1. XR_003953719.2 RNA Sequence

    2. XR_004940729.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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