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    Napg N-ethylmaleimide sensitive fusion protein attachment protein gamma [ Mus musculus (house mouse) ]

    Gene ID: 108123, updated on 9-Dec-2024

    Summary

    Official Symbol
    Napgprovided by MGI
    Official Full Name
    N-ethylmaleimide sensitive fusion protein attachment protein gammaprovided by MGI
    Primary source
    MGI:MGI:104561
    See related
    Ensembl:ENSMUSG00000024581 AllianceGenome:MGI:104561
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SNARE; 2400003O04Rik
    Summary
    Predicted to enable soluble NSF attachment protein activity and syntaxin binding activity. Predicted to be involved in intracellular protein transport. Located in myelin sheath. Is expressed in embryo. Orthologous to human NAPG (NSF attachment protein gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 25.8), frontal lobe adult (RPKM 24.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Napg in Genome Data Viewer
    Location:
    18 E1; 18 35.95 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (63110910..63132521)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (62977836..62999450)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41752 Neighboring gene adenomatosis polyposis coli down-regulated 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:63137389-63137586 Neighboring gene STARR-seq mESC enhancer starr_44784 Neighboring gene piezo-type mechanosensitive ion channel component 2 Neighboring gene predicted gene, 36651 Neighboring gene STARR-seq mESC enhancer starr_44785 Neighboring gene STARR-seq mESC enhancer starr_44786 Neighboring gene STARR-seq mESC enhancer starr_44787 Neighboring gene STARR-seq mESC enhancer starr_44788 Neighboring gene predicted gene, 26972

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables soluble NSF attachment protein activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables syntaxin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in myelin sheath HDA PubMed 
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    gamma-soluble NSF attachment protein
    Names
    N-ethylmaleimide-sensitive factor attachment protein gamma
    SNAP-gamma

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419376.1NP_001406305.1  gamma-soluble NSF attachment protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC140554
      UniProtKB/TrEMBL
      D3Z4B2
      Related
      ENSMUSP00000122681.2, ENSMUST00000150267.2
    2. NM_001419381.1NP_001406310.1  gamma-soluble NSF attachment protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC140554
      UniProtKB/TrEMBL
      A0A494BA20, A0A494BAE3
      Related
      ENSMUSP00000158047.2, ENSMUST00000235372.2
    3. NM_028017.2NP_082293.1  gamma-soluble NSF attachment protein isoform 1

      See identical proteins and their annotated locations for NP_082293.1

      Status: VALIDATED

      Source sequence(s)
      AC140554
      Consensus CDS
      CCDS29295.1
      UniProtKB/Swiss-Prot
      Q3TPT4, Q9CWZ7
      UniProtKB/TrEMBL
      Q8C1T5
      Related
      ENSMUSP00000025474.7, ENSMUST00000025474.14
      Conserved Domains (1) summary
      cd15832
      Location:8278
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      63110910..63132521
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246809.4XP_011245111.1  gamma-soluble NSF attachment protein isoform X3

      See identical proteins and their annotated locations for XP_011245111.1

      UniProtKB/TrEMBL
      A0A494BA20
      Conserved Domains (2) summary
      cd15832
      Location:2459
      SNAP; TPR repeat [structural motif]
      cl24038
      Location:5241
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family
    2. XM_011246807.3XP_011245109.1  gamma-soluble NSF attachment protein isoform X2

      UniProtKB/TrEMBL
      A0A494BA20
      Conserved Domains (2) summary
      cd15832
      Location:2964
      SNAP; TPR repeat [structural motif]
      cl24038
      Location:1246
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family
    3. XM_011246808.4XP_011245110.1  gamma-soluble NSF attachment protein isoform X3

      See identical proteins and their annotated locations for XP_011245110.1

      UniProtKB/TrEMBL
      A0A494BA20
      Conserved Domains (2) summary
      cd15832
      Location:2459
      SNAP; TPR repeat [structural motif]
      cl24038
      Location:5241
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family