C8h11orf65 similar to human chromosome 11 open reading frame 65 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: C8h11orf65provided by RGD
Official Full Name: similar to human chromosome 11 open reading frame 65provided by RGD
Primary source: RGD:1311251
See related: EnsemblRapid:ENSRNOG00000007266 AllianceGenome:RGD:1311251
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Mfi; RGD1311251
Summary: Predicted to be involved in negative regulation of mitochondrial fission and negative regulation of protein targeting to mitochondrion. Predicted to be located in cytosol and mitochondrial outer membrane. Orthologous to human C11orf65 (chromosome 11 open reading frame 65). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 91.4), Liver (RPKM 46.0) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q24

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (62692123..62720951)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (53796033..53825277)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (57983168..58012474)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH128975 (e-PCR)
- UniSTS:212283

D8RAT113 (e-PCR)
- UniSTS:120537

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in negative regulation of mitochondrial fission	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of mitochondrial fission	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of protein targeting to mitochondrion	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of protein targeting to mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: protein MFI

Names: mitochondrial fission factor interactor; protein C11orf65 homolog; uncharacterized protein C11orf65 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.