Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Sult2a2provided by RGD
Official Full Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2provided by RGD
Primary source: RGD:1306542
See related: EnsemblRapid:ENSRNOG00000062869 AllianceGenome:RGD:1306542
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: DST; SMP-2; ST2A2
Summary: Predicted to enable alcohol sulfotransferase activity. Predicted to be involved in steroid metabolic process. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 3412.4) See more
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Genomic context

Location:: 1q21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (85037518..85104532, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (75909585..75976600, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (76252329..76517193, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH94657 (e-PCR)
- UniSTS:119904

D1Wox13 (e-PCR)
- UniSTS:118118

D1Rat481 (e-PCR), detects polymorphism
- UniSTS:227263

D1Got74 (e-PCR)
- UniSTS:113865

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables alcohol sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables sulfotransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in steroid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sulfotransferase 2A2

Names: Androgen-repressible liver protein; Dehydroepiandrosterone sulfotransferase; Probable alcohol sulfotransferase; ST; ST-60; Senescence marker protein 2; alcohol sulfotransferase; alcohol sulfotransferase-like; hydroxysteroid sulfotransferase

NP_001020302.1

EC 2.8.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.