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    Kri1 KRI1 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 687183, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Kri1provided by RGD
    Official Full Name
    KRI1 homologprovided by RGD
    Primary source
    RGD:1588903
    See related
    EnsemblRapid:ENSRNOG00000057447 AllianceGenome:RGD:1588903
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in nucleolus. Orthologous to human KRI1 (KRI1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 139.1), Spleen (RPKM 122.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Kri1 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (28093175..28107576, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (19817005..19831516, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (22301025..22317049, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene Kelch-like ECH-associated protein 1 Neighboring gene sphingosine-1-phosphate receptor 5 Neighboring gene autophagy related 4D, cysteine peptidase Neighboring gene cyclin dependent kinase inhibitor 2D Neighboring gene adaptor related protein complex 1 subunit mu 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein KRI1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398706.1 → NP_001385635.1  protein KRI1 homolog

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JXS2
      Related
      ENSRNOP00000070383.2, ENSRNOT00000085605.3
      Conserved Domains (2) summary
      pfam05178
      Location:318 → 403
      Kri1; KRI1-like family
      pfam12936
      Location:494 → 582
      Kri1_C; KRI1-like family C-terminal

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      28093175..28107576 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082792.2 → XP_038938720.1  protein KRI1 homolog isoform X1

      Conserved Domains (2) summary
      pfam05178
      Location:317 → 402
      Kri1; KRI1-like family
      pfam12936
      Location:493 → 581
      Kri1_C; KRI1-like family C-terminal

    2. XM_063266154.1 → XP_063122224.1  protein KRI1 homolog isoform X2

    3. XM_039082794.2 → XP_038938722.1  protein KRI1 homolog isoform X2

      Conserved Domains (2) summary
      pfam05178
      Location:204 → 289
      Kri1; KRI1-like family
      pfam12936
      Location:380 → 468
      Kri1_C; KRI1-like family C-terminal

    4. XM_039082795.2 → XP_038938723.1  protein KRI1 homolog isoform X3

      Conserved Domains (1) summary
      pfam05178
      Location:318 → 396
      Kri1; KRI1-like family
    Nucleotide Protein Strain
    Heading Accession and Version

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