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    Poglut3 protein O-glucosyltransferase 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315664, updated on 9-Dec-2024

    Summary

    Official Symbol
    Poglut3provided by RGD
    Official Full Name
    protein O-glucosyltransferase 3provided by RGD
    Primary source
    RGD:1562027
    See related
    EnsemblRapid:ENSRNOG00000007177 AllianceGenome:RGD:1562027
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Kdelc2
    Summary
    Predicted to enable UDP-glucosyltransferase activity and UDP-xylosyltransferase activity. Predicted to be involved in protein O-linked glycosylation via serine. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endomembrane system. Orthologous to human POGLUT3 (protein O-glucosyltransferase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 177.7), Lung (RPKM 141.4) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Poglut3 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (62673811..62691606)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (53777614..53795404)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (57964988..57982605)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 10 Neighboring gene anaphase promoting complex subunit 15, pseudogene 1 Neighboring gene exophilin 5 Neighboring gene uncharacterized LOC120094158 Neighboring gene similar to human chromosome 11 open reading frame 65 Neighboring gene ATM serine/threonine kinase Neighboring gene uncharacterized LOC120094159

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables EGF-domain serine glucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables EGF-domain serine xylosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables UDP-glucosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables UDP-glucosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables UDP-xylosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables UDP-xylosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables glucosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation via serine ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein O-linked glycosylation via serine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein O-glucosyltransferase 3
    Names
    KDEL (Lys-Asp-Glu-Leu) containing 2
    KDEL motif containing 2
    KDEL motif-containing protein 2
    protein O-xylosyltransferase POGLUT3
    NP_001020294.3
    XP_063121533.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025123.3NP_001020294.3  protein O-glucosyltransferase 3 precursor

      See identical proteins and their annotated locations for NP_001020294.3

      Status: VALIDATED

      Source sequence(s)
      BC093594, BC100617, BU759576, JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q497C8, Q566E5
      UniProtKB/TrEMBL
      A6J4J1
      Related
      ENSRNOP00000009497.5, ENSRNOT00000009497.7
      Conserved Domains (2) summary
      cl23835
      Location:152486
      Glyco_transf_90; Glycosyl transferase family 90
      pfam00630
      Location:27131
      Filamin; Filamin/ABP280 repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      62673811..62691606
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265463.1XP_063121533.1  protein O-glucosyltransferase 3 isoform X1

    RNA

    1. XR_010053963.1 RNA Sequence