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    Snapc2 small nuclear RNA activating complex, polypeptide 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304204, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snapc2provided by RGD
    Official Full Name
    small nuclear RNA activating complex, polypeptide 2provided by RGD
    Primary source
    RGD:1304589
    See related
    EnsemblRapid:ENSRNOG00000001056 AllianceGenome:RGD:1304589
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA polymerase II general transcription initiation factor activity. Predicted to be involved in snRNA transcription and transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nuclear body. Orthologous to human SNAPC2 (small nuclear RNA activating complex polypeptide 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 114.4), Testes (RPKM 65.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snapc2 in Genome Data Viewer
    Location:
    12p12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (7403650..7406840)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (2605794..2608997)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (2537291..2540774, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene mitogen activated protein kinase kinase 7 Neighboring gene transforming growth factor beta receptor 3 like Neighboring gene uncharacterized LOC120095870 Neighboring gene cortexin 1 Neighboring gene translocase of inner mitochondrial membrane 44

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A structural perspective on RNA polymerase I and RNA polymerase III transcription machineries. Vannini A. Biochim Biophys Acta, 2013 Mar-Apr. PMID 23031840
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA polymerase II general transcription initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in snRNA transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    snRNA-activating protein complex subunit 2
    Names
    SNAPc 45 kDa subunit
    SNAPc subunit 2
    snRNA-activating protein complex 45 kDa subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013121.1 → NP_001013139.1  snRNA-activating protein complex subunit 2 isoform 1

      See identical proteins and their annotated locations for NP_001013139.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079077
      UniProtKB/Swiss-Prot
      Q68FX5
      UniProtKB/TrEMBL
      A6KQ68
      Conserved Domains (1) summary
      pfam11035
      Location:1 → 354
      SnAPC_2_like; Small nuclear RNA activating complex subunit 2, SNAP190 Myb

    2. NM_001415804.1 → NP_001402733.1  snRNA-activating protein complex subunit 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6KQ70
      Related
      ENSRNOP00000106639.1, ENSRNOT00000126086.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      7403650..7406840
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008768956.4 → XP_008767178.1  snRNA-activating protein complex subunit 2 isoform X1

      Related
      ENSRNOP00000001398.6, ENSRNOT00000001398.8
      Conserved Domains (1) summary
      pfam11035
      Location:1 → 371
      SnAPC_2_like; Small nuclear RNA activating complex subunit 2, SNAP190 Myb

    2. XM_039089313.2 → XP_038945241.1  snRNA-activating protein complex subunit 2 isoform X2

      Conserved Domains (1) summary
      pfam11035
      Location:6 → 298
      SnAPC_2_like; Small nuclear RNA activating complex subunit 2, SNAP190 Myb
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68FX5.1 GenPept UniProtKB/Swiss-Prot:Q68FX5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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