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    Thap6 THAP domain containing 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305244, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Thap6provided by RGD
    Official Full Name
    THAP domain containing 6provided by RGD
    Primary source
    RGD:1310094
    See related
    EnsemblRapid:ENSRNOG00000058724 AllianceGenome:RGD:1310094
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity. Predicted to be located in microtubule cytoskeleton. Orthologous to human THAP6 (THAP domain containing 6). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Muscle (RPKM 58.6), Heart (RPKM 53.3) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Thap6 in Genome Data Viewer
    Location:
    14p22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (16385579..16397735, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (16092919..16113528, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (17595865..17616192, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene Sec61 translocon subunit gamma, pseudogene 2 Neighboring gene cyclin dependent kinase like 2 Neighboring gene odontogenesis associated phosphoprotein Neighboring gene uncharacterized LOC102546535 Neighboring gene ring finger and CHY zinc finger domain containing 1 Neighboring gene uncharacterized LOC134481723 Neighboring gene uncharacterized LOC134481724

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in microtubule cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    THAP domain-containing protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107209.2 → NP_001100679.1  THAP domain-containing protein 6

      See identical proteins and their annotated locations for NP_001100679.1

      Status: VALIDATED

      Source sequence(s)
      CK602350, FM098768
      UniProtKB/TrEMBL
      A0A0G2K0Q4, A6KKB4
      Related
      ENSRNOP00000071541.1, ENSRNOT00000090938.3
      Conserved Domains (1) summary
      smart00980
      Location:4 → 89
      THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      16385579..16397735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017599174.2 → XP_017454663.1  THAP domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K0Q4, A6KKB4
      Conserved Domains (1) summary
      smart00980
      Location:4 → 89
      THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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