Abcg3l3 ATP-binding cassette, subfamily G (WHITE), member 3-like 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Abcg3l3provided by RGD
Official Full Name: ATP-binding cassette, subfamily G (WHITE), member 3-like 3provided by RGD
Primary source: RGD:1564709
See related: EnsemblRapid:ENSRNOG00000069246 AllianceGenome:RGD:1564709
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564709
Summary: Predicted to enable ATPase-coupled transmembrane transporter activity; efflux transmembrane transporter activity; and riboflavin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 81.6), Lung (RPKM 65.4) and 9 other tissues See more
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Genomic context

Location:: 14p22

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (5148826..5196890)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (4844161..4892194)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (5733361..6104164)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH139136 (e-PCR)
- UniSTS:221222

RH134993 (e-PCR)
- UniSTS:218270

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables efflux transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables riboflavin transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in riboflavin transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ATP-binding cassette, sub-family G (WHITE), member 3 family member

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107205.1 → NP_001100675.1 ATP-binding cassette, sub-family G (WHITE), member 3 family member

See identical proteins and their annotated locations for NP_001100675.1

Status: PROVISIONAL

Source sequence(s)

CH474022

UniProtKB/TrEMBL

A0A8I6A653, A0A8I6ACK9, A6K5Q8

Related

ENSRNOP00000089408.1, ENSRNOT00000093929.2

Conserved Domains (1) summary

TIGR00955
Location:64 → 644

3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086032.1 Reference GRCr8

Range

5148826..5196890

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039091819.2 → XP_038947747.1 ATP-binding cassette, sub-family G (WHITE), member 3 family member isoform X2

Conserved Domains (1) summary

TIGR00955
Location:64 → 487

3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
XM_063273045.1 → XP_063129115.1 ATP-binding cassette, sub-family G (WHITE), member 3 family member isoform X1
XM_039091817.2 → XP_038947745.1 ATP-binding cassette, sub-family G (WHITE), member 3 family member isoform X1

Conserved Domains (1) summary

TIGR00955
Location:3 → 514

3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein