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    Iqcd IQ motif containing D [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498184, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Iqcdprovided by RGD
    Official Full Name
    IQ motif containing Dprovided by RGD
    Primary source
    RGD:1560757
    See related
    EnsemblRapid:ENSRNOG00000087772 AllianceGenome:RGD:1560757
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in ciliary basal body. Orthologous to human IQCD (IQ motif containing D). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 55.9), Kidney (RPKM 38.6) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Iqcd in Genome Data Viewer
    Location:
    12q16
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (41616107..41633244, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (35955522..35972420, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (41490451..41507416, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 73 Neighboring gene DEAD-box helicase 54 Neighboring gene RBPJ interacting and tubulin associated 1 Neighboring gene uncharacterized LOC120095848 Neighboring gene two pore segment channel 1 Neighboring gene solute carrier family 8 member B1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dynein regulatory complex protein 10
    Names
    IQ domain-containing protein D

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402221.2 → NP_001389150.1  dynein regulatory complex protein 10

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/Swiss-Prot
      Q5XIR6
      UniProtKB/TrEMBL
      A0A8L2Q0W6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      41616107..41633244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_056984752.2 → XP_056840732.1  dynein regulatory complex protein 10 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A727

    2. XM_063271589.1 → XP_063127659.1  dynein regulatory complex protein 10 isoform X2

      UniProtKB/Swiss-Prot
      Q5XIR6
      UniProtKB/TrEMBL
      A0A8L2Q0W6
      Related
      ENSRNOP00000001860.4, ENSRNOT00000001860.7

    3. XM_063271591.1 → XP_063127661.1  dynein regulatory complex protein 10 isoform X4

      UniProtKB/TrEMBL
      A6J1I7

    4. XM_063271590.1 → XP_063127660.1  dynein regulatory complex protein 10 isoform X3

      UniProtKB/TrEMBL
      A6J1I7

    RNA

    1. XR_010056411.1 RNA Sequence

    2. XR_005491723.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001037361.1: Suppressed sequence

      Description
      NM_001037361.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XIR6.2 GenPept UniProtKB/Swiss-Prot:Q5XIR6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.