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    GRAMD1A GRAM domain containing 1A [ Bos taurus (domestic cattle) ]

    Gene ID: 507027, updated on 1-Jan-2025

    Summary

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    Official Symbol
    GRAMD1Aprovided by VGNC
    Official Full Name
    GRAM domain containing 1Aprovided by VGNC
    Primary source
    VGNC:VGNC:29622
    See related
    BGD:BT14968; Ensembl:ENSBTAG00000003820
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See GRAMD1A in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (45742837..45767893)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 792 Neighboring gene calmodulin pseudogene Neighboring gene sodium voltage-gated channel beta subunit 1 Neighboring gene hepsin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cholesterol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cholesterol transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular sterol transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum-plasma membrane contact site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein Aster-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305021.2 → NP_001291950.2  protein Aster-A

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      UniProtKB/TrEMBL
      A0A3Q1M539, A0AAA9TVV8
      Related
      ENSBTAP00000068760.2, ENSBTAT00000071456.2
      Conserved Domains (3) summary
      cd13220
      Location:102 → 195
      PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam16016
      Location:370 → 518
      DUF4782; Domain of unknown function (DUF4782)
      cl00713
      Location:255 → 358
      Auto_anti-p27; Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      45742837..45767893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005219085.5 → XP_005219142.2  protein Aster-A isoform X1

      UniProtKB/TrEMBL
      F6QVR0, Q1JPC6
      Related
      ENSBTAP00000004977.5, ENSBTAT00000004977.6
      Conserved Domains (3) summary
      cd13220
      Location:190 → 283
      PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam16016
      Location:458 → 606
      DUF4782; Domain of unknown function (DUF4782)
      cl25751
      Location:21 → 154
      DUF4045; Domain of unknown function (DUF4045)

    2. XM_059876560.1 → XP_059732543.1  protein Aster-A isoform X3

      UniProtKB/TrEMBL
      Q1JPC6

    3. XM_005219087.5 → XP_005219144.2  protein Aster-A isoform X2

      UniProtKB/TrEMBL
      A0AAA9TVV8
      Related
      ENSBTAP00000102476.1, ENSBTAT00000099607.1
      Conserved Domains (3) summary
      cd13220
      Location:102 → 195
      PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam16016
      Location:370 → 518
      DUF4782; Domain of unknown function (DUF4782)
      cl00713
      Location:255 → 358
      Auto_anti-p27; Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)

    4. XM_059876559.1 → XP_059732542.1  protein Aster-A isoform X3

      UniProtKB/TrEMBL
      Q1JPC6
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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