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    ANAPC5 anaphase promoting complex subunit 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 540537, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ANAPC5provided by VGNC
    Official Full Name
    anaphase promoting complex subunit 5provided by VGNC
    Primary source
    VGNC:VGNC:25885
    See related
    BGD:BT27718; Ensembl:ENSBTAG00000003092
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ANAPC5 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (53827416..53862505)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene lysine demethylase 2B Neighboring gene ring finger protein 34 Neighboring gene tetraspanin-33-like Neighboring gene calcium/calmodulin dependent protein kinase kinase 2 Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene purinergic receptor P2X 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of mitotic metaphase/anaphase transition IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K11-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    anaphase-promoting complex subunit 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192945.1 → NP_001179874.1  anaphase-promoting complex subunit 5

      See identical proteins and their annotated locations for NP_001179874.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000017
      UniProtKB/TrEMBL
      E1BK11
      Related
      ENSBTAP00000004025.5, ENSBTAT00000004025.6
      Conserved Domains (4) summary
      sd00016
      Location:248 → 282
      Apc5; TPR repeat [structural motif]
      sd00006
      Location:467 → 495
      TPR; TPR repeat [structural motif]
      cd16270
      Location:32 → 165
      Apc5_N; N-terminal domain of the anaphase-promoting complex subunit Apc5 (or Anapc5)
      pfam12862
      Location:254 → 354
      ANAPC5; Anaphase-promoting complex subunit 5

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53827416..53862505
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015475490.3 → XP_015330976.1  anaphase-promoting complex subunit 5 isoform X1

      Conserved Domains (3) summary
      sd00016
      Location:110 → 144
      Apc5; TPR repeat [structural motif]
      cd16270
      Location:1 → 27
      Apc5_N; N-terminal domain of the anaphase-promoting complex subunit Apc5 (or Anapc5)
      pfam12862
      Location:116 → 216
      ANAPC5; Anaphase-promoting complex subunit 5

    2. XM_059876134.1 → XP_059732117.1  anaphase-promoting complex subunit 5 isoform X1

    3. XM_024977410.2 → XP_024833178.1  anaphase-promoting complex subunit 5 isoform X1

      Conserved Domains (3) summary
      sd00016
      Location:110 → 144
      Apc5; TPR repeat [structural motif]
      cd16270
      Location:1 → 27
      Apc5_N; N-terminal domain of the anaphase-promoting complex subunit Apc5 (or Anapc5)
      pfam12862
      Location:116 → 216
      ANAPC5; Anaphase-promoting complex subunit 5

    4. XM_024977409.2 → XP_024833177.1  anaphase-promoting complex subunit 5 isoform X1

      Conserved Domains (3) summary
      sd00016
      Location:110 → 144
      Apc5; TPR repeat [structural motif]
      cd16270
      Location:1 → 27
      Apc5_N; N-terminal domain of the anaphase-promoting complex subunit Apc5 (or Anapc5)
      pfam12862
      Location:116 → 216
      ANAPC5; Anaphase-promoting complex subunit 5
    Nucleotide Protein Strain
    Heading Accession and Version

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