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    POFUT2 protein O-fucosyltransferase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 404083, updated on 27-Dec-2024

    Summary

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    Official Symbol
    POFUT2provided by VGNC
    Official Full Name
    protein O-fucosyltransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:33106
    See related
    BGD:BT11078; Ensembl:ENSBTAG00000007818
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    FUT13
    Orthologs
    human mouse all
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    Genomic context

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    See POFUT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (145089427..145103037, complement)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101906512 Neighboring gene adenosine deaminase RNA specific B1 Neighboring gene uncharacterized LOC112448009 Neighboring gene uncharacterized LOC101907800 Neighboring gene collagen type XVIII alpha 1 chain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of protein O-fucosyltransferase genes and splice variants. Loriol C, et al. Glycobiology, 2006 Aug. PMID 16679357
    2. A new superfamily of protein-O-fucosyltransferases, alpha2-fucosyltransferases, and alpha6-fucosyltransferases: phylogeny and identification of conserved peptide motifs. Martinez-Duncker I, et al. Glycobiology, 2003 Dec. PMID 12966037
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. cDNA sequences and genomic structure of POFUT2 are reported.
      Title: Molecular evolution of protein O-fucosyltransferase genes and splice variants.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables peptide-O-fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein O-linked fucosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GDP-fucose protein O-fucosyltransferase 2
    Names
    protein O-fucosyltransferase 2a
    protein O-fucosyltransferase 2c
    protein O-fucosyltransferase 2d
    protein O-fucosyltransferase 2e
    NP_991351.1
    XP_024850639.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205782.1 → NP_991351.1  GDP-fucose protein O-fucosyltransferase 2 precursor

      See identical proteins and their annotated locations for NP_991351.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ575655
      UniProtKB/TrEMBL
      Q7YRE5, Q7YRR5
      Related
      ENSBTAP00000010281.5, ENSBTAT00000010281.6
      Conserved Domains (2) summary
      cd11298
      Location:45 → 414
      O-FucT-2; GDP-fucose protein O-fucosyltransferase 2
      pfam10250
      Location:50 → 408
      O-FucT; GDP-fucose protein O-fucosyltransferase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      145089427..145103037 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024994871.2 → XP_024850639.1  GDP-fucose protein O-fucosyltransferase 2 isoform X1

      Conserved Domains (1) summary
      cd11298
      Location:45 → 284
      O-FucT-2; GDP-fucose protein O-fucosyltransferase 2
    Nucleotide Protein Strain
    Heading Accession and Version

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