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    MAP2K2 mitogen-activated protein kinase kinase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 510434, updated on 27-Dec-2024

    Summary

    Official Symbol
    MAP2K2provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:55215
    See related
    BGD:BT25071; Ensembl:ENSBTAG00000024450
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See MAP2K2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (19909636..19930988)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene cAMP responsive element binding protein 3 like 3 Neighboring gene uncharacterized LOC132345829 Neighboring gene zinc finger and BTB domain containing 7A Neighboring gene protein inhibitor of activated STAT 4

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC134398, MGC140486

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    dual specificity mitogen-activated protein kinase kinase 2
    NP_001033160.2
    XP_005208988.3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038071.2NP_001033160.2  dual specificity mitogen-activated protein kinase kinase 2

      See identical proteins and their annotated locations for NP_001033160.2

      Status: PROVISIONAL

      Source sequence(s)
      BC118362
      UniProtKB/TrEMBL
      A0A3S5ZPX3, F1MYR6, Q17QH2
      Related
      ENSBTAP00000063221.1, ENSBTAT00000081829.2
      Conserved Domains (1) summary
      cd06649
      Location:66396
      PKc_MEK2; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase 2

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      19909636..19930988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005208931.5XP_005208988.3  dual specificity mitogen-activated protein kinase kinase 2 isoform X1