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    APCDD1 APC down-regulated 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 509040, updated on 30-Jan-2025

    Summary

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    Official Symbol
    APCDD1provided by VGNC
    Official Full Name
    APC down-regulated 1provided by VGNC
    Primary source
    VGNC:VGNC:26007
    See related
    BGD:BT22615; EnsemblRapid:ENSBTAG00070023790
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See APCDD1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (42127482..42172485)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene VAMP associated protein A Neighboring gene uncharacterized LOC104975774 Neighboring gene uncharacterized LOC132343776 Neighboring gene uncharacterized LOC132343777 Neighboring gene NSF attachment protein gamma Neighboring gene piezo type mechanosensitive ion channel component 2 Neighboring gene uncharacterized LOC112444160

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Wnt-protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein APCDD1
    Names
    adenomatosis polyposis coli down-regulated 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42127482..42172485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024984412.2 → XP_024840180.1  protein APCDD1 isoform X1

      UniProtKB/TrEMBL
      F1MNJ4
      Related
      ENSBTAP00070032151.1, ENSBTAT00070053518.1
      Conserved Domains (1) summary
      pfam14921
      Location:51 → 282
      APCDDC; Adenomatosis polyposis coli down-regulated 1

    2. XM_002697746.6 → XP_002697792.1  protein APCDD1 isoform X2

      See identical proteins and their annotated locations for XP_002697792.1

      Conserved Domains (1) summary
      pfam14921
      Location:1 → 228
      APCDDC; Adenomatosis polyposis coli down-regulated 1
    Nucleotide Protein Strain
    Heading Accession and Version

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