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    RNF123 ring finger protein 123 [ Bos taurus (domestic cattle) ]

    Gene ID: 514160, updated on 30-Jan-2025

    Summary

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    Official Symbol
    RNF123provided by VGNC
    Official Full Name
    ring finger protein 123provided by VGNC
    Primary source
    VGNC:VGNC:34016
    See related
    BGD:BT25243; EnsemblRapid:ENSBTAG00070036042
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RNF123 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (50484030..50512625, complement)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene cadherin related family member 4 Neighboring gene inositol hexakisphosphate kinase 1 Neighboring gene GDP-mannose pyrophosphorylase B Neighboring gene adhesion molecule with Ig like domain 3 Neighboring gene macrophage stimulating 1 Neighboring gene acylaminoacyl-peptide hydrolase Neighboring gene bassoon presynaptic cytomatrix protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF123
    NP_001179993.1
    XP_005222848.1
    XP_005222849.1
    XP_010816006.1
    XP_010816008.1
    XP_024838408.1
    XP_024838409.1
    XP_024838411.1
    XP_059735598.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193064.1 → NP_001179993.1  E3 ubiquitin-protein ligase RNF123

      See identical proteins and their annotated locations for NP_001179993.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000022
      UniProtKB/TrEMBL
      A0AAA9TM68, E1BL26
      Related
      ENSBTAP00070048955.1, ENSBTAT00070080802.1
      Conserved Domains (2) summary
      cd12882
      Location:124 → 251
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1251 → 1291
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      50484030..50512625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879615.1 → XP_059735598.1  E3 ubiquitin-protein ligase RNF123 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TM68, E1BL26
      Related
      ENSBTAP00070048961.1, ENSBTAT00070080808.1

    2. XM_005222792.5 → XP_005222849.1  E3 ubiquitin-protein ligase RNF123 isoform X1

      See identical proteins and their annotated locations for XP_005222849.1

      UniProtKB/TrEMBL
      A0AAA9TM68, E1BL26
      Related
      ENSBTAP00070048968.1, ENSBTAT00070080815.1
      Conserved Domains (2) summary
      cd12882
      Location:124 → 251
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1251 → 1291
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    3. XM_024982640.2 → XP_024838408.1  E3 ubiquitin-protein ligase RNF123 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TM68, E1BL26
      Conserved Domains (2) summary
      cd12882
      Location:124 → 251
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1251 → 1291
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    4. XM_005222791.5 → XP_005222848.1  E3 ubiquitin-protein ligase RNF123 isoform X1

      See identical proteins and their annotated locations for XP_005222848.1

      UniProtKB/TrEMBL
      A0AAA9TM68, E1BL26
      Related
      ENSBTAP00070048946.1, ENSBTAT00070080792.1
      Conserved Domains (2) summary
      cd12882
      Location:124 → 251
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1251 → 1291
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    5. XM_010817704.4 → XP_010816006.1  E3 ubiquitin-protein ligase RNF123 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TM68
      Conserved Domains (2) summary
      cd12882
      Location:124 → 251
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1221 → 1261
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    6. XM_024982641.2 → XP_024838409.1  E3 ubiquitin-protein ligase RNF123 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TM68, E1BL26
      Conserved Domains (2) summary
      cd12882
      Location:124 → 251
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1251 → 1291
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    7. XM_024982643.2 → XP_024838411.1  E3 ubiquitin-protein ligase RNF123 isoform X3

      UniProtKB/TrEMBL
      A0AAA9TM68
      Conserved Domains (2) summary
      cd16541
      Location:1104 → 1144
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins
      cl02614
      Location:1 → 104
      SPRY; SPRY domain

    8. XM_010817706.4 → XP_010816008.1  E3 ubiquitin-protein ligase RNF123 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TM68
      Conserved Domains (2) summary
      pfam13920
      Location:1043 → 1091
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
      cl02614
      Location:8 → 45
      SPRY; SPRY domain
    Nucleotide Protein Strain
    Heading Accession and Version

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