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    AASS aminoadipate-semialdehyde synthase [ Bos taurus (domestic cattle) ]

    Gene ID: 520865, updated on 30-Jan-2025

    Summary

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    Official Symbol
    AASSprovided by VGNC
    Official Full Name
    aminoadipate-semialdehyde synthaseprovided by VGNC
    Primary source
    VGNC:VGNC:25451
    See related
    BGD:BT18318; EnsemblRapid:ENSBTAG00070028876
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See AASS in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (86512542..86594657, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345187 Neighboring gene protein tyrosine phosphatase receptor type Z1 Neighboring gene small ribosomal subunit protein uS5-like Neighboring gene chromobox protein homolog 3-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC166100

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables saccharopine dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process via aminoadipic acid IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-aminoadipic semialdehyde synthase, mitochondrial
    Names
    LKR/SDH
    NP_001103267.1
    XP_024846466.1
    XP_059741588.1
    XP_059741589.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109797.1 → NP_001103267.1  alpha-aminoadipic semialdehyde synthase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001103267.1

      Status: PROVISIONAL

      Source sequence(s)
      BC153851
      UniProtKB/Swiss-Prot
      A8E657
      UniProtKB/TrEMBL
      A0AAF6YXC0
      Related
      ENSBTAP00070039717.1, ENSBTAT00070065636.1
      Conserved Domains (2) summary
      cd12189
      Location:25 → 466
      LKR_SDH_like; bifunctional lysine ketoglutarate reductase /saccharopine dehydrogenase enzyme
      cl25613
      Location:25 → 916
      Sacchrp_dh_C; Saccharopine dehydrogenase C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      86512542..86594657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024990698.2 → XP_024846466.1  alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X2

      UniProtKB/Swiss-Prot
      A8E657
      UniProtKB/TrEMBL
      A0AAF6YXC0
      Conserved Domains (2) summary
      cd12189
      Location:25 → 466
      LKR_SDH_like; bifunctional lysine ketoglutarate reductase /saccharopine dehydrogenase enzyme
      cl25613
      Location:25 → 916
      Sacchrp_dh_C; Saccharopine dehydrogenase C-terminal domain

    2. XM_059885606.1 → XP_059741589.1  alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X2

      UniProtKB/Swiss-Prot
      A8E657
      UniProtKB/TrEMBL
      A0AAF6YXC0

    3. XM_059885605.1 → XP_059741588.1  alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0AAF6YXC0
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8E657.1 GenPept UniProtKB/Swiss-Prot:A8E657

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