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    DHCR7 7-dehydrocholesterol reductase [ Bos taurus (domestic cattle) ]

    Gene ID: 514745, updated on 30-Jan-2025

    Summary

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    Official Symbol
    DHCR7provided by VGNC
    Official Full Name
    7-dehydrocholesterol reductaseprovided by VGNC
    Primary source
    VGNC:VGNC:28034
    See related
    BGD:BT23247; EnsemblRapid:ENSBTAG00070037157
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See DHCR7 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (48285095..48304736, complement)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene actin epsilon 1 Neighboring gene uncharacterized LOC132344215 Neighboring gene NAD synthetase 1 Neighboring gene mas-related G-protein coupled receptor member B5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 7-dehydrocholesterol reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in brassinosteroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    7-dehydrocholesterol reductase
    Names
    7-DHC reductase
    sterol Delta(7)-reductase
    NP_001014927.1
    XP_024842887.1
    XP_024842888.1
    XP_024842889.1
    XP_024842890.1
    XP_059738887.1
    XP_059738888.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014927.1 → NP_001014927.1  7-dehydrocholesterol reductase

      See identical proteins and their annotated locations for NP_001014927.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020925
      UniProtKB/Swiss-Prot
      A6QR24, Q5E9J5
      Related
      ENSBTAP00070050259.1, ENSBTAT00070083114.1
      Conserved Domains (1) summary
      cl21511
      Location:93 → 475
      PEMT; Phospholipid methyltransferase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      48285095..48304736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024987119.2 → XP_024842887.1  7-dehydrocholesterol reductase isoform X1

      UniProtKB/Swiss-Prot
      A6QR24, Q5E9J5
      Conserved Domains (1) summary
      cl21511
      Location:93 → 475
      PEMT; Phospholipid methyltransferase

    2. XM_024987122.2 → XP_024842890.1  7-dehydrocholesterol reductase isoform X1

      UniProtKB/Swiss-Prot
      A6QR24, Q5E9J5
      Conserved Domains (1) summary
      cl21511
      Location:93 → 475
      PEMT; Phospholipid methyltransferase

    3. XM_024987120.2 → XP_024842888.1  7-dehydrocholesterol reductase isoform X1

      UniProtKB/Swiss-Prot
      A6QR24, Q5E9J5
      Conserved Domains (1) summary
      cl21511
      Location:93 → 475
      PEMT; Phospholipid methyltransferase

    4. XM_059882904.1 → XP_059738887.1  7-dehydrocholesterol reductase isoform X1

      UniProtKB/Swiss-Prot
      A6QR24, Q5E9J5

    5. XM_024987121.2 → XP_024842889.1  7-dehydrocholesterol reductase isoform X1

      UniProtKB/Swiss-Prot
      A6QR24, Q5E9J5
      Conserved Domains (1) summary
      cl21511
      Location:93 → 475
      PEMT; Phospholipid methyltransferase

    6. XM_059882905.1 → XP_059738888.1  7-dehydrocholesterol reductase isoform X1

      UniProtKB/Swiss-Prot
      A6QR24, Q5E9J5
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5E9J5.1 GenPept UniProtKB/Swiss-Prot:Q5E9J5

    Gene LinkOut

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