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    SPARCL1 SPARC like 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 507537, updated on 30-Jan-2025

    Summary

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    Official Symbol
    SPARCL1provided by VGNC
    Official Full Name
    SPARC like 1provided by VGNC
    Primary source
    VGNC:VGNC:35172
    See related
    BGD:BT15171; EnsemblRapid:ENSBTAG00070023832
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SPARCL1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (102370630..102423199, complement)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene josephin-1-like pseudogene Neighboring gene nudix hydrolase 9 Neighboring gene uncharacterized LOC132345541 Neighboring gene uncharacterized LOC104968931 Neighboring gene dentin sialophosphoprotein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127494

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables collagen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables extracellular matrix binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SPARC-like protein 1
    Names
    SPARC-like 1 (hevin)
    SPARC-like 1 (mast9, hevin)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034302.2 → NP_001029474.1  SPARC-like protein 1 precursor

      See identical proteins and their annotated locations for NP_001029474.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103351
      UniProtKB/TrEMBL
      A0A3Q1LIS3, Q3SYW7
      Related
      ENSBTAP00070032207.1, ENSBTAT00070053626.1
      Conserved Domains (4) summary
      cd00252
      Location:504 → 652
      SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
      pfam05029
      Location:32 → 277
      TIMELESS_C; Timeless protein C terminal region
      pfam10591
      Location:503 → 638
      SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
      cl00097
      Location:423 → 502
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      102370630..102423199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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