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    RAC3 Rac family small GTPase 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 619066, updated on 1-Jan-2025

    Summary

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    Official Symbol
    RAC3provided by VGNC
    Official Full Name
    Rac family small GTPase 3provided by VGNC
    Primary source
    VGNC:VGNC:55865
    See related
    BGD:BT16787; Ensembl:ENSBTAG00000022927
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RAC3 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (50876771..50880197, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101910153 Neighboring gene dicarbonyl and L-xylulose reductase Neighboring gene leucine rich repeat containing 45 Neighboring gene centromere protein X Neighboring gene ASPSCR1 tether for SLC2A4, UBX domain containing Neighboring gene uncharacterized LOC132343110 Neighboring gene microRNA mir-2346

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC166020

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cortical cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in engulfment of apoptotic cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment or maintenance of cell polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in motor neuron axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras-related C3 botulinum toxin substrate 3
    Names
    ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
    NP_001092649.1
    XP_024836274.1
    XP_024836275.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099179.2 → NP_001092649.1  ras-related C3 botulinum toxin substrate 3

      See identical proteins and their annotated locations for NP_001092649.1

      Status: PROVISIONAL

      Source sequence(s)
      BC142381
      UniProtKB/TrEMBL
      A5PK69, F1MCR0, F1MNG3
      Related
      ENSBTAP00000031119.5, ENSBTAT00000031159.5
      Conserved Domains (1) summary
      cd01871
      Location:3 → 176
      Rac1_like; Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-like consists of Rac1, Rac2 and Rac3

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      50876771..50880197 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024980506.2 → XP_024836274.1  ras-related C3 botulinum toxin substrate 3 isoform X1

      UniProtKB/TrEMBL
      A5PK69, F1MCR0, F1MNG3
      Conserved Domains (1) summary
      cd01871
      Location:3 → 176
      Rac1_like; Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-like consists of Rac1, Rac2 and Rac3

    2. XM_024980507.2 → XP_024836275.1  ras-related C3 botulinum toxin substrate 3 isoform X2

      Conserved Domains (1) summary
      cl21455
      Location:3 → 150
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version

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