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    GNGT1 G protein subunit gamma transducin 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 281796, updated on 30-Jan-2025

    Summary

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    Official Symbol
    GNGT1provided by VGNC
    Official Full Name
    G protein subunit gamma transducin 1provided by VGNC
    Primary source
    VGNC:VGNC:29470
    See related
    BGD:BT28808; EnsemblRapid:ENSBTAG00070001375
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See GNGT1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (11210171..11235219)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene tissue factor pathway inhibitor 2 Neighboring gene G protein subunit gamma 11 Neighboring gene Bet1 golgi vesicular membrane trafficking protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Partial cDNA sequence of the gamma subunit of transducin. Van Dop C, et al. Biochem Biophys Res Commun, 1984 Oct 15. PMID 6149748
    2. Complete amino acid sequence of gamma-subunit of the GTP-binding protein from cattle retina. Ovchinnikov YuA, et al. FEBS Lett, 1985 Jan 1. PMID 3917402
    3. cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments. Yatsunami K, et al. Proc Natl Acad Sci U S A, 1985 Apr. PMID 2984674, Free PMC Article
    4. Farnesylated gamma-subunit of photoreceptor G protein indispensable for GTP-binding. Fukada Y, et al. Nature, 1990 Aug 16. PMID 2385292
    5. The gamma subunit of transducin is farnesylated. Lai RK, et al. Proc Natl Acad Sci U S A, 1990 Oct. PMID 2217200, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The PIP2-induced orientation of the GRK2-Gbeta1gamma2 complex is therefore most likely caused by specific interactions between PIP2 and the GRK2 PH domain.
      Title: Effect of Lipid Composition on the Membrane Orientation of the G Protein-Coupled Receptor Kinase 2-Gβ1γ2 Complex.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(T) subunit gamma-T1
    Names
    guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
    transducin gamma chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174327.3 → NP_776752.1  guanine nucleotide-binding protein G(T) subunit gamma-T1

      See identical proteins and their annotated locations for NP_776752.1

      Status: VALIDATED

      Source sequence(s)
      K03255
      UniProtKB/Swiss-Prot
      P02698
      Related
      ENSBTAP00070001906.1, ENSBTAT00070003201.1
      Conserved Domains (1) summary
      smart00224
      Location:12 → 74
      GGL; G protein gamma subunit-like motifs

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      11210171..11235219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024990465.2 → XP_024846233.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

      Conserved Domains (1) summary
      smart00224
      Location:18 → 80
      GGL; G protein gamma subunit-like motifs

    2. XM_010803983.4 → XP_010802285.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X2

      See identical proteins and their annotated locations for XP_010802285.1

      UniProtKB/Swiss-Prot
      P02698
      Conserved Domains (1) summary
      smart00224
      Location:12 → 74
      GGL; G protein gamma subunit-like motifs
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P02698.2 GenPept UniProtKB/Swiss-Prot:P02698

    Gene LinkOut

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