U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    IMPA1 inositol monophosphatase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 281865, updated on 1-Feb-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    IMPA1provided by VGNC
    Official Full Name
    inositol monophosphatase 1provided by VGNC
    Primary source
    VGNC:VGNC:30184
    See related
    BGD:BT20268
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See IMPA1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (80890935..80922355)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene charged multivesicular body protein 4C Neighboring gene uncharacterized LOC100335514 Neighboring gene zinc finger AN1-type containing 1 Neighboring gene solute carrier family 10 member 5 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 2 Neighboring gene microRNA mir-2285n-6 Neighboring gene uncharacterized LOC104974144

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. High-resolution structure of myo-inositol monophosphatase, the putative target of lithium therapy. Gill R, et al. Acta Crystallogr D Biol Crystallogr, 2005 May. PMID 15858264
    2. Cloning and expression of bovine brain inositol monophosphatase. Diehl RE, et al. J Biol Chem, 1990 Apr 15. PMID 1690719
    3. Brain inositol monophosphatase identified as a galactose 1-phosphatase. Parthasarathy R, et al. Brain Res, 1997 Dec 5. PMID 9462881
    4. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC140630

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol monophosphate 1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inositol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    inositol monophosphatase 1
    Names
    D-galactose 1-phosphate phosphatase
    IMP 1
    IMPase 1
    inositol(myo)-1(or 4)-monophosphatase 1
    inositol-1(or 4)-monophosphatase 1
    lithium-sensitive myo-inositol monophosphatase A1
    NP_776786.1
    XP_005215709.1
    XP_015330016.1
    XP_059749106.1
    XP_059749107.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174361.4 → NP_776786.1  inositol monophosphatase 1

      See identical proteins and their annotated locations for NP_776786.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118411
      UniProtKB/Swiss-Prot
      P20456, Q17QE4
      UniProtKB/TrEMBL
      A5D9H1
      Conserved Domains (1) summary
      cd01639
      Location:8 → 254
      IMPase; inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      80890935..80922355
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059893123.1 → XP_059749106.1  inositol monophosphatase 1 isoform X1

      UniProtKB/TrEMBL
      A5D9H1

    2. XM_015474530.3 → XP_015330016.1  inositol monophosphatase 1 isoform X2

      UniProtKB/Swiss-Prot
      P20456, Q17QE4
      UniProtKB/TrEMBL
      A5D9H1
      Conserved Domains (1) summary
      cd01639
      Location:8 → 254
      IMPase; inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled ...

    3. XM_005215652.5 → XP_005215709.1  inositol monophosphatase 1 isoform X2

      See identical proteins and their annotated locations for XP_005215709.1

      UniProtKB/Swiss-Prot
      P20456, Q17QE4
      UniProtKB/TrEMBL
      A5D9H1
      Conserved Domains (1) summary
      cd01639
      Location:8 → 254
      IMPase; inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled ...

    4. XM_059893124.1 → XP_059749107.1  inositol monophosphatase 1 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20456.1 GenPept UniProtKB/Swiss-Prot:P20456

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.