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    SOAT2 sterol O-acyltransferase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 513554, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SOAT2provided by VGNC
    Official Full Name
    sterol O-acyltransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:35117
    See related
    BGD:BT28715; Ensembl:ENSBTAG00000005623
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SOAT2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (26867423..26877789, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene integrin subunit beta 7 Neighboring gene zinc finger protein 740 Neighboring gene cysteine sulfinic acid decarboxylase Neighboring gene insulin like growth factor binding protein 6 Neighboring gene SPRY domain containing 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC179401

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cholesterol O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cholesterol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol efflux IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cholesterol homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cholesterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sterol O-acyltransferase 2
    NP_001095446.1
    XP_010803204.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101976.2 → NP_001095446.1  sterol O-acyltransferase 2

      See identical proteins and their annotated locations for NP_001095446.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151492
      UniProtKB/TrEMBL
      A0A3Q1LV59, A7MBD0
      Related
      ENSBTAP00000061260.1, ENSBTAT00000084437.2
      Conserved Domains (1) summary
      pfam03062
      Location:162 → 507
      MBOAT; MBOAT, membrane-bound O-acyltransferase family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      26867423..26877789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010804902.4 → XP_010803204.1  sterol O-acyltransferase 2 isoform X1

      See identical proteins and their annotated locations for XP_010803204.1

      UniProtKB/TrEMBL
      A0A3Q1LV59, F1N277
      Related
      ENSBTAP00000007392.5, ENSBTAT00000007392.6
      Conserved Domains (1) summary
      pfam03062
      Location:166 → 511
      MBOAT; MBOAT, membrane-bound O-acyltransferase family
    Nucleotide Protein Strain
    Heading Accession and Version

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