U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RAD50 RAD50 double strand break repair protein [ Bos taurus (domestic cattle) ]

    Gene ID: 788127, updated on 30-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    RAD50provided by VGNC
    Official Full Name
    RAD50 double strand break repair proteinprovided by VGNC
    Primary source
    VGNC:VGNC:52870
    See related
    BGD:BT16302; EnsemblRapid:ENSBTAG00070002606
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RAD50 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (21765852..22018104, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene interleukin 4 Neighboring gene interleukin 13 Neighboring gene interleukin 5 Neighboring gene uncharacterized LOC132345719 Neighboring gene interferon regulatory factor 1 Neighboring gene solute carrier family 22 member 5 Neighboring gene solute carrier family 22 member 4 Neighboring gene microRNA mir-2457

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G-quadruplex DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chromosome organization involved in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance via recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance via telomerase IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Mre11 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in condensed nuclear chromosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA repair protein RAD50
    Names
    RAD50 homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206868.1 → NP_001193797.1  DNA repair protein RAD50

      See identical proteins and their annotated locations for NP_001193797.1

      Status: VALIDATED

      Source sequence(s)
      BE682215, BI537119, DN531362, DT888981, DV910092, DY074672, DY195085, EE218707, EV732287, NKLS02000007
      UniProtKB/TrEMBL
      A0AAA9SC96, G3X6W2
      Related
      ENSBTAP00070003505.1, ENSBTAT00070006049.1
      Conserved Domains (3) summary
      TIGR00606
      Location:2 → 1312
      rad50; rad50
      cd03240
      Location:1195 → 1297
      ABC_Rad50; ATP-binding cassette domain of Rad50
      pfam04423
      Location:659 → 709
      Rad50_zn_hook; Rad50 zinc hook motif

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      21765852..22018104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059888479.1 → XP_059744462.1  DNA repair protein RAD50 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SC96

    2. XM_059888481.1 → XP_059744464.1  DNA repair protein RAD50 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SC96

    3. XM_059888480.1 → XP_059744463.1  DNA repair protein RAD50 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SC96
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.