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    ARHGEF40 Rho guanine nucleotide exchange factor 40 [ Bos taurus (domestic cattle) ]

    Gene ID: 527362, updated on 27-Dec-2024

    Summary

    Official Symbol
    ARHGEF40provided by VGNC
    Official Full Name
    Rho guanine nucleotide exchange factor 40provided by VGNC
    Primary source
    VGNC:VGNC:26118
    See related
    Ensembl:ENSBTAG00000013401
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See ARHGEF40 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (26001808..26020994, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AU member 1 Neighboring gene transmembrane protein 253 Neighboring gene zinc finger protein 219 Neighboring gene ribonuclease 7 Neighboring gene uncharacterized LOC104973100

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General protein information

    Preferred Names
    rho guanine nucleotide exchange factor 40
    Names
    Rho guanine nucleotide exchange factor (GEF) 40
    protein SOLO

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205941.1NP_001192870.1  rho guanine nucleotide exchange factor 40

      See identical proteins and their annotated locations for NP_001192870.1

      Status: PROVISIONAL

      Source sequence(s)
      AAFC03073382, AAFC03100398
      UniProtKB/TrEMBL
      F1MB21, G3MXG4
      Related
      ENSBTAP00000054231.3, ENSBTAT00000063701.3
      Conserved Domains (4) summary
      cd13242
      Location:12451380
      PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
      pfam00169
      Location:12701368
      PH; PH domain
      cl02488
      Location:785971
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02571
      Location:10871246
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      26001808..26020994 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)