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    ABCG4 ATP binding cassette subfamily G member 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 508443, updated on 1-Jan-2025

    Summary

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    Official Symbol
    ABCG4provided by VGNC
    Official Full Name
    ATP binding cassette subfamily G member 4provided by VGNC
    Primary source
    VGNC:VGNC:25484
    See related
    BGD:BT20532; Ensembl:ENSBTAG00000011800
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ABCG4 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (29730757..29745436)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene C2CD2 like Neighboring gene histone H4 transcription factor Neighboring gene NLR family member X1 Neighboring gene NHERF family PDZ scaffold protein 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ABC-type sterol transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol efflux IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cholesterol homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-binding cassette sub-family G member 4
    Names
    ATP-binding cassette, sub-family G (WHITE), member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105343.1 → NP_001098813.1  ATP-binding cassette sub-family G member 4

      See identical proteins and their annotated locations for NP_001098813.1

      Status: PROVISIONAL

      Source sequence(s)
      BC153242
      UniProtKB/TrEMBL
      A0A3Q1MQJ6, A7Z044
      Related
      ENSBTAP00000015667.5, ENSBTAT00000015667.6
      Conserved Domains (1) summary
      cl28180
      Location:44 → 646
      PRK10535; macrolide transporter ATP-binding /permease protein; Provisional

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29730757..29745436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059874621.1 → XP_059730604.1  ATP-binding cassette sub-family G member 4 isoform X3

    2. XM_010812438.4 → XP_010810740.1  ATP-binding cassette sub-family G member 4 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MQJ6
      Conserved Domains (3) summary
      TIGR03608
      Location:76 → 270
      L_ocin_972_ABC; putative bacteriocin export ABC transporter, lactococcin 972 group
      cd03213
      Location:58 → 283
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      pfam01061
      Location:377 → 572
      ABC2_membrane; ABC-2 type transporter

    3. XM_005215928.4 → XP_005215985.1  ATP-binding cassette sub-family G member 4 isoform X1

      See identical proteins and their annotated locations for XP_005215985.1

      UniProtKB/TrEMBL
      A0A3Q1MQJ6, A7Z044
      Conserved Domains (1) summary
      cl28180
      Location:44 → 646
      PRK10535; macrolide transporter ATP-binding /permease protein; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version

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