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    AKT1S1 AKT1 substrate 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 514859, updated on 30-Jan-2025

    Summary

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    Official Symbol
    AKT1S1provided by VGNC
    Official Full Name
    AKT1 substrate 1provided by VGNC
    Primary source
    VGNC:VGNC:25798
    See related
    BGD:BT15570; EnsemblRapid:ENSBTAG00070037171
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See AKT1S1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (56216992..56225206, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene fuzzy planar cell polarity protein Neighboring gene mediator complex subunit 25 Neighboring gene PTOV1 extended AT-hook containing adaptor protein Neighboring gene polynucleotide kinase 3'-phosphatase Neighboring gene TBC1 domain family member 17 Neighboring gene uncharacterized LOC107131441 Neighboring gene interleukin 4 induced 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC148526

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in negative regulation of TOR signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotrophin TRK receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proline-rich AKT1 substrate 1
    Names
    AKT1 substrate 1 (proline-rich)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083434.2 → NP_001076903.1  proline-rich AKT1 substrate 1

      See identical proteins and their annotated locations for NP_001076903.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133618
      UniProtKB/TrEMBL
      A0AAA9TU40, A3KN52
      Related
      ENSBTAP00070050285.1, ENSBTAT00070083140.1
      Conserved Domains (1) summary
      pfam15798
      Location:127 → 251
      PRAS; Proline-rich AKT1 substrate 1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      56216992..56225206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005219263.5 → XP_005219320.1  proline-rich AKT1 substrate 1 isoform X1

      See identical proteins and their annotated locations for XP_005219320.1

      UniProtKB/TrEMBL
      A0AAA9TU40
      Conserved Domains (1) summary
      pfam15798
      Location:127 → 251
      PRAS; Proline-rich AKT1 substrate 1

    2. XM_059876684.1 → XP_059732667.1  proline-rich AKT1 substrate 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TU40

    3. XM_059876683.1 → XP_059732666.1  proline-rich AKT1 substrate 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TU40

    4. XM_005219262.5 → XP_005219319.1  proline-rich AKT1 substrate 1 isoform X1

      See identical proteins and their annotated locations for XP_005219319.1

      UniProtKB/TrEMBL
      A0AAA9TU40
      Conserved Domains (1) summary
      pfam15798
      Location:127 → 251
      PRAS; Proline-rich AKT1 substrate 1
    Nucleotide Protein Strain
    Heading Accession and Version

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