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    PAX8 paired box 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 534661, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PAX8provided by VGNC
    Official Full Name
    paired box 8provided by VGNC
    Primary source
    VGNC:VGNC:32599
    See related
    BGD:BT13297; Ensembl:ENSBTAG00000019354
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PAX8 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (46916025..46981270, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene interleukin 1 receptor antagonist Neighboring gene pleckstrin and Sec7 domain containing 4 Neighboring gene uncharacterized LOC132346580 Neighboring gene uncharacterized LOC132346581 Neighboring gene uncharacterized LOC132346582

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Physical mapping of the bovine, caprine and ovine homologues of the paired box gene PAX8. Lòpez-Corrales NL, et al. Cytogenet Cell Genet, 1999. PMID 10393423
    2. Refinement of bovine chromosome 2 linkage map near the mh locus reveals rearrangements between the bovine and human genomes. Sonstegard TS, et al. Anim Genet, 1998 Oct. PMID 9800322
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    paired box protein Pax-8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46916025..46981270 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005212819.5 → XP_005212876.1  paired box protein Pax-8 isoform X4

      See identical proteins and their annotated locations for XP_005212876.1

      UniProtKB/TrEMBL
      A0A3Q1MTI2
      Conserved Domains (2) summary
      smart00351
      Location:9 → 134
      PAX; Paired Box domain
      pfam12403
      Location:278 → 387
      Pax2_C; Paired-box protein 2 C terminal

    2. XM_005212816.5 → XP_005212873.1  paired box protein Pax-8 isoform X3

      See identical proteins and their annotated locations for XP_005212873.1

      UniProtKB/TrEMBL
      A0A3Q1MTI2
      Related
      ENSBTAP00000073625.1, ENSBTAT00000080819.2
      Conserved Domains (2) summary
      smart00351
      Location:9 → 134
      PAX; Paired Box domain
      pfam12403
      Location:345 → 422
      Pax2_C; Paired-box protein 2 C terminal

    3. XM_005212820.5 → XP_005212877.1  paired box protein Pax-8 isoform X5

      See identical proteins and their annotated locations for XP_005212877.1

      UniProtKB/TrEMBL
      A0A3Q1LK45, A0A3Q1MTI2
      Related
      ENSBTAP00000056867.1, ENSBTAT00000082376.2
      Conserved Domains (2) summary
      smart00351
      Location:9 → 133
      PAX; Paired Box domain
      pfam12403
      Location:277 → 386
      Pax2_C; Paired-box protein 2 C terminal

    4. XM_002691400.7 → XP_002691446.2  paired box protein Pax-8 isoform X2

      See identical proteins and their annotated locations for XP_002691446.2

      UniProtKB/TrEMBL
      A0A3Q1MTI2, F1MLH9
      Related
      ENSBTAP00000025783.6, ENSBTAT00000025783.7
      Conserved Domains (2) summary
      smart00351
      Location:9 → 133
      PAX; Paired Box domain
      pfam12403
      Location:344 → 455
      Pax2_C; Paired-box protein 2 C terminal

    5. XM_005212815.5 → XP_005212872.1  paired box protein Pax-8 isoform X1

      See identical proteins and their annotated locations for XP_005212872.1

      UniProtKB/TrEMBL
      A0A3Q1MTI2
      Conserved Domains (2) summary
      smart00351
      Location:9 → 134
      PAX; Paired Box domain
      pfam12403
      Location:345 → 456
      Pax2_C; Paired-box protein 2 C terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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