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    U2AF1 U2 small nuclear RNA auxiliary factor 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 512680, updated on 30-Jan-2025

    Summary

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    Gene symbol
    U2AF1
    Gene description
    U2 small nuclear RNA auxiliary factor 1
    See related
    BGD:BT16461; EnsemblRapid:ENSBTAG00070032351
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See U2AF1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (143261989..143274955, complement)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345932 Neighboring gene PBX/knotted 1 homeobox 1 Neighboring gene cystathionine beta-synthase Neighboring gene crystallin alpha A Neighboring gene uncharacterized LOC112448267

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC151885

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pre-mRNA 3'-splice site binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U2AF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing factor U2AF 35 kDa subunit
    Names
    U2 auxiliary factor 35 kDa subunit
    U2 snRNP auxiliary factor small subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080268.2 → NP_001073737.1  splicing factor U2AF 35 kDa subunit

      See identical proteins and their annotated locations for NP_001073737.1

      Status: PROVISIONAL

      Source sequence(s)
      BC126638
      UniProtKB/Swiss-Prot
      A1A4K8
      Related
      ENSBTAP00070044596.1, ENSBTAT00070073209.1
      Conserved Domains (2) summary
      pfam00642
      Location:149 → 175
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cd12538
      Location:43 → 146
      RRM_U2AF35; RNA recognition motif (RRM) found in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      143261989..143274955 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202017.5 → XP_005202074.1  splicing factor U2AF 35 kDa subunit isoform X1

      See identical proteins and their annotated locations for XP_005202074.1

      UniProtKB/TrEMBL
      A0A3Q1M895
      Related
      ENSBTAP00070044616.1, ENSBTAT00070073237.1
      Conserved Domains (2) summary
      pfam00642
      Location:149 → 175
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cd12538
      Location:43 → 146
      RRM_U2AF35; RNA recognition motif (RRM) found in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1A4K8.1 GenPept UniProtKB/Swiss-Prot:A1A4K8

    Gene LinkOut

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