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    DDX1 DEAD-box helicase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 510816, updated on 30-Jan-2025

    Summary

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    Official Symbol
    DDX1provided by VGNC
    Official Full Name
    DEAD-box helicase 1provided by VGNC
    Primary source
    VGNC:VGNC:27955
    See related
    BGD:BT15817; EnsemblRapid:ENSBTAG00070007049
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See DDX1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (82677432..82717536, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene transfer RNA leucine (anticodon GAG) Neighboring gene MYCN proto-oncogene, bHLH transcription factor Neighboring gene NBAS subunit of NRZ tethering complex Neighboring gene secretoglobin family 1C member 1 Neighboring gene outer dense fiber of sperm tails 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC139331

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase DDX1
    Names
    DEAD (Asp-Glu-Ala-Asp) box helicase 1
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
    DEAD box protein 1
    DEAD/H-box helicase 1
    NP_001068936.1
    XP_059747147.1
    XP_059747148.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075468.1 → NP_001068936.1  ATP-dependent RNA helicase DDX1

      See identical proteins and their annotated locations for NP_001068936.1

      Status: PROVISIONAL

      Source sequence(s)
      BC122599
      UniProtKB/Swiss-Prot
      Q0IIK5
      UniProtKB/TrEMBL
      A0A452DIC5
      Related
      ENSBTAP00070009129.1, ENSBTAT00070016027.1
      Conserved Domains (4) summary
      COG0513
      Location:284 → 624
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      pfam00271
      Location:493 → 609
      Helicase_C; Helicase conserved C-terminal domain
      cd12873
      Location:93 → 245
      SPRY_DDX1; SPRY domain associated with DEAD box gene DDX1
      cl21455
      Location:284 → 426
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      82677432..82717536 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891164.1 → XP_059747147.1  ATP-dependent RNA helicase DDX1 isoform X1

      UniProtKB/TrEMBL
      A0A452DIC5, A7E3W7
      Related
      ENSBTAP00070009156.1, ENSBTAT00070016065.1

    2. XM_059891165.1 → XP_059747148.1  ATP-dependent RNA helicase DDX1 isoform X2

      UniProtKB/Swiss-Prot
      Q0IIK5
      UniProtKB/TrEMBL
      A0A452DIC5
      Related
      ENSBTAP00070009143.1, ENSBTAT00070016048.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0IIK5.1 GenPept UniProtKB/Swiss-Prot:Q0IIK5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials