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    ATG16L1 autophagy related 16 like 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 509587, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ATG16L1provided by VGNC
    Official Full Name
    autophagy related 16 like 1provided by VGNC
    Primary source
    VGNC:VGNC:26253
    See related
    BGD:BT16113; Ensembl:ENSBTAG00000003928
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ATG16L1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (112968427..113012711)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene neuraminidase 2 Neighboring gene inositol polyphosphate-5-phosphatase D Neighboring gene small Cajal body-specific RNA 6 Neighboring gene small Cajal body-specific RNA 6 Neighboring gene S-antigen visual arrestin Neighboring gene diacylglycerol kinase delta Neighboring gene ubiquitin specific peptidase 40

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative stranded viral RNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in autophagosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    autophagy-related protein 16-1
    Names
    ATG16 autophagy related 16-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191389.2 → NP_001178318.1  autophagy-related protein 16-1

      See identical proteins and their annotated locations for NP_001178318.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000003
      UniProtKB/TrEMBL
      A0A3Q1M3D1
      Related
      ENSBTAP00000068004.1, ENSBTAT00000076323.1
      Conserved Domains (4) summary
      cd00200
      Location:317 → 605
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:327 → 364
      7WD40; WD40 repeat [structural motif]
      pfam08614
      Location:31 → 206
      ATG16; Autophagy protein 16 (ATG16)
      cl01837
      Location:212 → 257
      DUF2332; Uncharacterized protein conserved in bacteria (DUF2332)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      112968427..113012711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059883197.1 → XP_059739180.1  autophagy-related protein 16-1 isoform X2

    2. XM_005204950.5 → XP_005205007.1  autophagy-related protein 16-1 isoform X4

      See identical proteins and their annotated locations for XP_005205007.1

      UniProtKB/TrEMBL
      E1BGS8
      Related
      ENSBTAP00000005131.5, ENSBTAT00000005131.7
      Conserved Domains (4) summary
      cd00200
      Location:333 → 621
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:343 → 380
      7WD40; WD40 repeat [structural motif]
      pfam08614
      Location:31 → 206
      ATG16; Autophagy protein 16 (ATG16)
      pfam09787
      Location:95 → 336
      Golgin_A5; Golgin subfamily A member 5

    3. XM_005204951.5 → XP_005205008.1  autophagy-related protein 16-1 isoform X5

      See identical proteins and their annotated locations for XP_005205008.1

      UniProtKB/TrEMBL
      A0A3Q1LZW5
      Related
      ENSBTAP00000061276.1, ENSBTAT00000075306.2
      Conserved Domains (4) summary
      cd00200
      Location:298 → 586
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:308 → 345
      7WD40; WD40 repeat [structural motif]
      pfam08614
      Location:31 → 206
      ATG16; Autophagy protein 16 (ATG16)
      cl01837
      Location:212 → 269
      DUF2332; Uncharacterized protein conserved in bacteria (DUF2332)

    4. XM_059883204.1 → XP_059739187.1  autophagy-related protein 16-1 isoform X6

    5. XM_059883196.1 → XP_059739179.1  autophagy-related protein 16-1 isoform X1

    6. XM_059883198.1 → XP_059739181.1  autophagy-related protein 16-1 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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