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    OPA1 OPA1 mitochondrial dynamin like GTPase [ Bos taurus (domestic cattle) ]

    Gene ID: 524142, updated on 27-Dec-2024

    Summary

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    Official Symbol
    OPA1provided by VGNC
    Official Full Name
    OPA1 mitochondrial dynamin like GTPaseprovided by VGNC
    Primary source
    VGNC:VGNC:32432
    See related
    BGD:BT22234; Ensembl:ENSBTAG00000019514
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See OPA1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (73769819..73856381, complement)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene hes family bHLH transcription factor 1 Neighboring gene uncharacterized LOC104970902 Neighboring gene uncharacterized LOC112447410 Neighboring gene uncharacterized LOC104970904 Neighboring gene ATPase 13A4 Neighboring gene microRNA mir-2285bk

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dynamin-like GTPase OPA1, mitochondrial
    Names
    optic atrophy 1 homolog
    NP_001179890.1
    XP_005201556.1
    XP_005201557.1
    XP_005201558.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192961.1 → NP_001179890.1  dynamin-like GTPase OPA1, mitochondrial

      See identical proteins and their annotated locations for NP_001179890.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      A0A3Q1LJL3, A0AAA9TNV9
      Related
      ENSBTAP00000059634.1, ENSBTAT00000082852.1
      Conserved Domains (1) summary
      cd08771
      Location:324 → 598
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      73769819..73856381 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005201501.5 → XP_005201558.1  dynamin-like GTPase OPA1, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0AAA9TZX0
      Conserved Domains (1) summary
      cd08771
      Location:287 → 561
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    2. XM_005201500.5 → XP_005201557.1  dynamin-like GTPase OPA1, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0AAA9TF64, A0AAA9TZX0
      Related
      ENSBTAP00000096761.1, ENSBTAT00000129412.1
      Conserved Domains (1) summary
      cd08771
      Location:305 → 579
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    3. XM_005201499.5 → XP_005201556.1  dynamin-like GTPase OPA1, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0AAA9S306, A0AAA9TNV9
      Related
      ENSBTAP00000079474.1, ENSBTAT00000095238.1
      Conserved Domains (1) summary
      cd08771
      Location:342 → 616
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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