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    Ceacam16 CEA cell adhesion molecule 16, tectorial membrane component [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292700, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ceacam16provided by RGD
    Official Full Name
    CEA cell adhesion molecule 16, tectorial membrane componentprovided by RGD
    Primary source
    RGD:1306386
    See related
    EnsemblRapid:ENSRNOG00000031391 AllianceGenome:RGD:1306386
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in sensory perception of sound. Predicted to be located in extracellular space and stereocilium tip. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 4B and autosomal recessive nonsyndromic deafness 113. Orthologous to human CEACAM16 (CEA cell adhesion molecule 16, tectorial membrane component). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 59.7), Testes (RPKM 11.7) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Ceacam16 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88642925..88652821, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79514975..79524871, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80773819..80783898, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene Cbl proto-oncogene C Neighboring gene BCL3, transcription coactivator Neighboring gene uncharacterized LOC134482896 Neighboring gene CEA cell adhesion molecule 19 Neighboring gene PVR cell adhesion molecule

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in sensory perception of sound IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sensory perception of sound IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within sensory perception of sound ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sensory perception of sound ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sensory perception of sound ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in stereocilium tip IEA
    Inferred from Electronic Annotation
    more info
     
    located_in stereocilium tip ISO
    Inferred from Sequence Orthology
    more info
     
    located_in stereocilium tip ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    cell adhesion molecule CEACAM16; carcinoembryonic antigen-related cell adhesion molecule 16
    Names
    B-cell leukemia/lymphoma 3
    CEA-related cell adhesion molecule 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001169579.1NP_001163050.1  cell adhesion molecule CEACAM16 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      D3ZQE1
      UniProtKB/TrEMBL
      A0A0A0MY19
      Related
      ENSRNOP00000041331.4, ENSRNOT00000045306.6
      Conserved Domains (5) summary
      cd05774
      Location:24128
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00410
      Location:144220
      IG_like; Immunoglobulin like
      pfam07679
      Location:224313
      I-set; Immunoglobulin I-set domain
      pfam13895
      Location:248311
      Ig_2; Immunoglobulin domain
      cl11960
      Location:140220
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      88642925..88652821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283214.1XP_063139284.1  carcinoembryonic antigen-related cell adhesion molecule 16 isoform X1