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    Mettl24 methyltransferase like 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499465, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mettl24provided by RGD
    Official Full Name
    methyltransferase like 24provided by RGD
    Primary source
    RGD:1564857
    See related
    EnsemblRapid:ENSRNOG00000024221 AllianceGenome:RGD:1564857
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in extracellular region. Orthologous to human METTL24 (methyltransferase like 24). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 61.9), Adrenal (RPKM 44.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mettl24 in Genome Data Viewer
    Location:
    20q12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (45724506..45847300)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (44142126..44264651)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (48586322..48706793, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 16 Neighboring gene D-aspartate oxidase Neighboring gene uncharacterized LOC120098819 Neighboring gene uncharacterized LOC120098955 Neighboring gene cell division cycle 40 Neighboring gene WASP family member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable methyltransferase-like protein 24
    Names
    UPF0624 protein C6orf186 homolog
    methyltransferase-like protein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025038.1 → NP_001020209.1  probable methyltransferase-like protein 24 precursor

      See identical proteins and their annotated locations for NP_001020209.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091261
      UniProtKB/Swiss-Prot
      Q5BK01
      UniProtKB/TrEMBL
      A6KTC3
      Related
      ENSRNOP00000038872.3, ENSRNOT00000036766.7
      Conserved Domains (1) summary
      cl17173
      Location:170 → 330
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      45724506..45847300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099027.2 → XP_038954955.1  probable methyltransferase-like protein 24 isoform X1

    2. XM_039099028.2 → XP_038954956.1  probable methyltransferase-like protein 24 isoform X2

    3. XM_039099029.2 → XP_038954957.1  probable methyltransferase-like protein 24 isoform X3

    4. XM_039099030.1 → XP_038954958.1  probable methyltransferase-like protein 24 isoform X4

      Conserved Domains (1) summary
      cl17173
      Location:29 → 154
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RNA

    1. XR_005497329.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BK01.1 GenPept UniProtKB/Swiss-Prot:Q5BK01

    Gene LinkOut

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