U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zkscan7 zinc finger with KRAB and SCAN domains 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363170, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    Zkscan7provided by RGD
    Official Full Name
    zinc finger with KRAB and SCAN domains 7provided by RGD
    Primary source
    RGD:1305242
    See related
    EnsemblRapid:ENSRNOG00000004104 AllianceGenome:RGD:1305242
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp167; Znf167
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZKSCAN7 (zinc finger with KRAB and SCAN domains 7). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Kidney (RPKM 22.8), Heart (RPKM 18.2) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Zkscan7 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (131379514..131397065)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (122501938..122519600)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (131932753..131968550)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 3 open reading frame 86 Neighboring gene zinc finger protein 445 Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger protein 660 Neighboring gene zinc finger protein 105

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC189403

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    zinc finger protein with KRAB and SCAN domains 7
    Names
    zinc finger protein 167

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170577.3 → NP_001164048.1  zinc finger protein with KRAB and SCAN domains 7

      See identical proteins and their annotated locations for NP_001164048.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      E9PTG0
      Related
      ENSRNOP00000051121.5, ENSRNOT00000043784.6
      Conserved Domains (7) summary
      smart00431
      Location:46 → 156
      SCAN; leucine rich region
      COG5048
      Location:353 → 707
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:550 → 570
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:442 → 462
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:492 → 514
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:46 → 133
      SCAN; SCAN domain
      pfam13465
      Location:506 → 531
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      131379514..131397065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017595774.3 → XP_017451263.1  zinc finger protein with KRAB and SCAN domains 7 isoform X1

    2. XM_006244199.3 → XP_006244261.1  zinc finger protein with KRAB and SCAN domains 7 isoform X2

      See identical proteins and their annotated locations for XP_006244261.1

      UniProtKB/TrEMBL
      E9PTG0
      Conserved Domains (7) summary
      smart00431
      Location:46 → 156
      SCAN; leucine rich region
      COG5048
      Location:353 → 707
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:550 → 570
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:442 → 462
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:492 → 514
      zf-C2H2; Zinc finger, C2H2 type
      pfam02023
      Location:46 → 133
      SCAN; SCAN domain
      pfam13465
      Location:506 → 531
      zf-H2C2_2; Zinc-finger double domain

    3. XM_063265857.1 → XP_063121927.1  zinc finger protein with KRAB and SCAN domains 7 isoform X4

    4. XM_039081822.2 → XP_038937750.1  zinc finger protein with KRAB and SCAN domains 7 isoform X3

      Conserved Domains (2) summary
      COG5048
      Location:102 → 456
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:299 → 319
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous