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    Snx29 sorting nexin 29 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689142, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snx29provided by RGD
    Official Full Name
    sorting nexin 29provided by RGD
    Primary source
    RGD:1596162
    See related
    EnsemblRapid:ENSRNOG00000002294 AllianceGenome:RGD:1596162
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rundc2a; RGD1565890
    Summary
    Predicted to enable phosphatidylinositol binding activity. Orthologous to several human genes including SNX29 (sorting nexin 29). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 203.2), Adrenal (RPKM 64.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snx29 in Genome Data Viewer
    Location:
    10q11
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (4391866..4805682, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (3884880..4298699, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (3838444..4249741, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene shisa family member 9 Neighboring gene uncharacterized LOC120095014 Neighboring gene calcineurin-like phosphoesterase domain containing 1 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene uncharacterized LOC120095243 Neighboring gene uncharacterized LOC134480744 Neighboring gene TNF receptor superfamily member 17 Neighboring gene uncharacterized LOC120095016 Neighboring gene G1 to S phase transition 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The Phox (PX) domain proteins and membrane traffic. Seet LF, et al. Biochim Biophys Acta, 2006 Aug. PMID 16782399
    2. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sorting nexin-29
    Names
    RUN domain containing 2A
    RUN domain-containing protein 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109526.2 → NP_001102996.2  sorting nexin-29

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6A5K5, D3ZMN5
      Related
      ENSRNOP00000086300.2, ENSRNOT00000112304.2
      Conserved Domains (4) summary
      cd07277
      Location:661 → 778
      PX_RUN; The phosphoinositide binding Phox Homology domain of uncharacterized proteins containing PX and RUN domains
      COG1340
      Location:469 → 634
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam02759
      Location:44 → 179
      RUN; RUN domain
      pfam10211
      Location:465 → 544
      Ax_dynein_light; Axonemal dynein light chain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      4391866..4805682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086859.2 → XP_038942787.1  sorting nexin-29 isoform X3

      UniProtKB/TrEMBL
      D3ZMN5
      Conserved Domains (3) summary
      cd07277
      Location:605 → 722
      PX_RUN; The phosphoinositide binding Phox Homology domain of uncharacterized proteins containing PX and RUN domains
      COG1340
      Location:413 → 578
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam02759
      Location:1 → 121
      RUN; RUN domain

    2. XM_039086858.1 → XP_038942786.1  sorting nexin-29 isoform X2

      UniProtKB/TrEMBL
      D3ZMN5
      Conserved Domains (3) summary
      COG1340
      Location:489 → 654
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam02759
      Location:64 → 197
      RUN; RUN domain
      cl02563
      Location:681 → 751
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    3. XM_039086860.1 → XP_038942788.1  sorting nexin-29 isoform X4

      UniProtKB/TrEMBL
      D3ZMN5
      Conserved Domains (2) summary
      cd07277
      Location:597 → 714
      PX_RUN; The phosphoinositide binding Phox Homology domain of uncharacterized proteins containing PX and RUN domains
      COG1340
      Location:405 → 570
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]

    4. XM_039086857.2 → XP_038942785.1  sorting nexin-29 isoform X1

      UniProtKB/TrEMBL
      D3ZMN5
      Related
      ENSRNOP00000107115.1, ENSRNOT00000167540.1
      Conserved Domains (3) summary
      cd07277
      Location:681 → 798
      PX_RUN; The phosphoinositide binding Phox Homology domain of uncharacterized proteins containing PX and RUN domains
      COG1340
      Location:489 → 654
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam02759
      Location:64 → 197
      RUN; RUN domain

    5. XM_063269879.1 → XP_063125949.1  sorting nexin-29 isoform X8

    6. XM_039086867.2 → XP_038942795.1  sorting nexin-29 isoform X11

      Conserved Domains (2) summary
      cd07277
      Location:459 → 576
      PX_RUN; The phosphoinositide binding Phox Homology domain of uncharacterized proteins containing PX and RUN domains
      COG1196
      Location:269 → 431
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    7. XM_008767499.4 → XP_008765721.1  sorting nexin-29 isoform X12

      See identical proteins and their annotated locations for XP_008765721.1

      UniProtKB/TrEMBL
      A0A8I5ZQH2, A6K4H0, A6K4H1
      Related
      ENSRNOP00000080569.1, ENSRNOT00000101337.2
      Conserved Domains (2) summary
      cd07277
      Location:319 → 436
      PX_RUN; The phosphoinositide binding Phox Homology domain of uncharacterized proteins containing PX and RUN domains
      pfam10211
      Location:123 → 202
      Ax_dynein_light; Axonemal dynein light chain

    8. XM_039086861.2 → XP_038942789.1  sorting nexin-29 isoform X5

      UniProtKB/TrEMBL
      D3ZMN5
      Conserved Domains (3) summary
      COG1340
      Location:489 → 654
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam02759
      Location:64 → 197
      RUN; RUN domain
      cl02563
      Location:681 → 702
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    9. XM_039086862.2 → XP_038942790.1  sorting nexin-29 isoform X6

      UniProtKB/TrEMBL
      D3ZMN5
      Conserved Domains (3) summary
      COG1340
      Location:489 → 654
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam02759
      Location:64 → 197
      RUN; RUN domain
      cl02563
      Location:681 → 707
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    10. XM_039086863.2 → XP_038942791.1  sorting nexin-29 isoform X7

      UniProtKB/TrEMBL
      D3ZMN5
      Conserved Domains (3) summary
      COG1340
      Location:489 → 654
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam02759
      Location:64 → 197
      RUN; RUN domain
      cl02563
      Location:681 → 702
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    11. XM_039086865.2 → XP_038942793.1  sorting nexin-29 isoform X10

      Conserved Domains (1) summary
      pfam02759
      Location:64 → 197
      RUN; RUN domain

    12. XM_039086864.2 → XP_038942792.1  sorting nexin-29 isoform X9

      Conserved Domains (2) summary
      pfam02759
      Location:64 → 197
      RUN; RUN domain
      cl27170
      Location:470 → 595
      DUF460; Protein of unknown function (DUF460)

    RNA

    1. XR_005489945.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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