Kif2b kinesin family member 2B [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Kif2bprovided by RGD
Full Name: kinesin family member 2Bprovided by RGD
Primary source: RGD:1359248
See related: EnsemblRapid:ENSRNOG00000086201 AllianceGenome:RGD:1359248
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in several processes, including metaphase chromosome alignment; microtubule depolymerization; and regulation of chromosome segregation. Predicted to be located in intercellular bridge; mitotic spindle; and nucleolus. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule cytoskeleton. Orthologous to human KIF2B (kinesin family member 2B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: 10q26

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (76891199..76893418, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (76394160..76396379, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (79095588..79097807, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule motor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in metaphase chromosome alignment	ISO Inferred from Sequence Orthology more info
involved_in metaphase chromosome alignment	ISS Inferred from Sequence or Structural Similarity more info
involved_in microtubule depolymerization	ISO Inferred from Sequence Orthology more info
involved_in microtubule depolymerization	ISS Inferred from Sequence or Structural Similarity more info
involved_in microtubule-based movement	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of chromosome segregation	ISO Inferred from Sequence Orthology more info
involved_in regulation of chromosome segregation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in centrosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in intercellular bridge	ISO Inferred from Sequence Orthology more info
part_of kinesin complex	IBA Inferred from Biological aspect of Ancestor more info
located_in kinetochore	IEA Inferred from Electronic Annotation more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in mitotic spindle	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
is_active_in spindle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: kinesin-like protein KIF2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.