Tmem86b transmembrane protein 86B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tmem86bprovided by RGD
Official Full Name: transmembrane protein 86Bprovided by RGD
Primary source: RGD:1593455
See related: EnsemblRapid:ENSRNOG00000087324 AllianceGenome:RGD:1593455
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Enables alkenylglycerophosphocholine hydrolase activity. Predicted to be involved in ether lipid metabolic process. Located in membrane. Orthologous to human TMEM86B (transmembrane protein 86B). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 232.5), Spleen (RPKM 60.9) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q12

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (78246869..78249235)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (69218109..69220474)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (72784147..72807768)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables D-lysine 5,6-aminomutase activity	IBA Inferred from Biological aspect of Ancestor more info
enables D-lysine 5,6-aminomutase activity	ISO Inferred from Sequence Orthology more info
enables D-lysine 5,6-aminomutase activity	ISS Inferred from Sequence or Structural Similarity more info
enables alkenylglycerophosphocholine hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alkenylglycerophosphocholine hydrolase activity	IDA Inferred from Direct Assay more info	PubMed
enables alkenylglycerophosphocholine hydrolase activity	ISO Inferred from Sequence Orthology more info
enables alkenylglycerophosphocholine hydrolase activity	ISS Inferred from Sequence or Structural Similarity more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in ether lipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ether lipid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in ether lipid metabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: lysoplasmalogenase TMEM86B

Names: lysoplasmalogenase

NP_001103074.1

EC 3.3.2.2

XP_063130864.1

EC 3.3.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.