Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ugt2a3provided by MGI
Official Full Name: UDP glucuronosyltransferase 2 family, polypeptide A3provided by MGI
Primary source: MGI:MGI:1919344
See related: Ensembl:ENSMUSG00000035780 AllianceGenome:MGI:1919344
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2010321J07Rik
Summary: Predicted to enable glucuronosyltransferase activity. Predicted to be involved in cellular glucuronidation. Predicted to be located in membrane. Is expressed in nervous system; nose; and olfactory epithelium. Orthologous to human UGT2A3 (UDP glucuronosyltransferase family 2 member A3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in liver adult (RPKM 48.1), duodenum adult (RPKM 5.4) and 2 other tissues See more
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Genomic context

Location:: 5 E1; 5 43.56 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (87472694..87485054, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (87324972..87337195, complement)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables glucuronosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucuronosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glucuronosyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular glucuronidation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-glucuronosyltransferase 2A3

Names: UDPGT 2A3

NP_082370.2

EC 2.4.1.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_028094.4 → NP_082370.2 UDP-glucuronosyltransferase 2A3 precursor

See identical proteins and their annotated locations for NP_082370.2

Status: VALIDATED

Source sequence(s)

AC101835

Consensus CDS

CCDS19387.1

UniProtKB/Swiss-Prot

Q8BWQ1, Q8R129, Q9D811

Related

ENSMUSP00000031195.3, ENSMUST00000031195.3

Conserved Domains (2) summary

PHA03392
Location:268 → 507

egt; ecdysteroid UDP-glucosyltransferase; Provisional

pfam00201
Location:25 → 526

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase