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    UBP8 ubiquitin-specific protease 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832263, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBP8
    Official Full Name
    ubiquitin-specific protease 8
    Primary source
    TAIR:AT5G22030
    Locus tag
    AT5G22030
    See related
    Araport:AT5G22030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ubiquitin-specific protease 8
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    Genomic context

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    See UBP8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (7289703..7296344, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RING-H2 group F2A Neighboring gene replication factor C1 Neighboring gene Calcium-dependent phosphotriesterase superfamily protein Neighboring gene ubiquitin carboxyl-terminal hydrolase Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001343718.1
    NM_122126.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-specific protease 8
    NP_001318617.1
    • ubiquitin-specific protease 8 (UBP8); FUNCTIONS IN: ubiquitin-specific protease activity, ubiquitin thiolesterase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 5 (TAIR:AT2G40930.1); Has 10748 Blast hits to 7392 proteins in 262 species: Archae - 0; Bacteria - 6; Metazoa - 5718; Fungi - 1753; Plants - 1297; Viruses - 10; Other Eukaryotes - 1964 (source: NCBI BLink).
    NP_568411.4
    • ubiquitin-specific protease 8 (UBP8); FUNCTIONS IN: ubiquitin-specific protease activity, ubiquitin thiolesterase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 5 (TAIR:AT2G40930.1); Has 10748 Blast hits to 7392 proteins in 262 species: Archae - 0; Bacteria - 6; Metazoa - 5718; Fungi - 1753; Plants - 1297; Viruses - 10; Other Eukaryotes - 1964 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7289703..7296344 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122126.5 → NP_568411.4  ubiquitin-specific protease 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568411.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y6E4, A0A7G2FE67
      Conserved Domains (3) summary
      COG5560
      Location:168 → 910
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:739 → 909
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl02553
      Location:321 → 497
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

    2. NM_001343718.1 → NP_001318617.1  ubiquitin-specific protease 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K8E0, Q0WVQ0, Q9C585, Q9FPT2
      UniProtKB/TrEMBL
      A0A178UPQ0, A0A5S9Y6E4, A0A7G2FE67
      Conserved Domains (1) summary
      COG5560
      Location:101 → 868
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C585.2

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