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    SQP2 squalene monooxygenase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832479, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SQP2
    Official Full Name
    squalene monooxygenase 2
    Primary source
    TAIR:AT5G24140
    Locus tag
    AT5G24140
    See related
    Araport:AT5G24140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MLE8.6; MLE8_6; squalene monooxygenase 2
    Summary
    Encodes a protein with similarity to squalene monoxygenases.
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    Genomic context

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    See SQP2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (8164319..8167776, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene sigma factor E Neighboring gene polypyrimidine tract-binding-like protein Neighboring gene FAD/NAD(P)-binding oxidoreductase family protein Neighboring gene FAD/NAD(P)-binding oxidoreductase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An example of intron junctional sliding in the gene families encoding squalene monooxygenase homologues in Arabidopsis thaliana and Brassica napus. Schäfer UA, et al. Plant Mol Biol, 1999 Mar. PMID 10350086
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_122319.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables squalene monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sterol biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    squalene monooxygenase 2
    NP_197802.2
    • squalene monooxygenase 2 (SQP2); FUNCTIONS IN: squalene monooxygenase activity, oxidoreductase activity, FAD binding; INVOLVED IN: sterol biosynthetic process; LOCATED IN: endomembrane system, integral to membrane; EXPRESSED IN: root; CONTAINS InterPro DOMAIN/s: Squalene epoxidase (InterPro:IPR013698), FAD dependent oxidoreductase (InterPro:IPR006076); BEST Arabidopsis thaliana protein match is: FAD/NAD(P)-binding oxidoreductase family protein (TAIR:AT5G24150.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8164319..8167776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122319.4 → NP_197802.2  squalene monooxygenase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65403
      UniProtKB/TrEMBL
      A0A2H1ZE80, A0A5S9Y7B2
    Nucleotide Protein
    Heading Accession and Version

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