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    Vmo1 vitelline membrane outer layer 1 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360553, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vmo1provided by RGD
    Official Full Name
    vitelline membrane outer layer 1 homologprovided by RGD
    Primary source
    RGD:1559861
    See related
    EnsemblRapid:ENSRNOG00000026508 AllianceGenome:RGD:1559861
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559861
    Summary
    Predicted to be active in extracellular space. Orthologous to human VMO1 (vitelline membrane outer layer 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 8.4), Lung (RPKM 6.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Vmo1 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55726572..55733432, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (55227944..55234794, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (57120499..57121584, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene zinc finger, MYND-type containing 15 Neighboring gene transmembrane 4 L six family member 5 Neighboring gene glycolipid transfer protein domain containing 2 Neighboring gene chromosome 10 C17orf114 homolog Neighboring gene proteasome 20S subunit beta 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
    2. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article
    3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vitelline membrane outer layer protein 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191823.1 → NP_001178752.1  vitelline membrane outer layer protein 1 homolog precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      D3ZP97
      Related
      ENSRNOP00000034203.4, ENSRNOT00000029421.6
      Conserved Domains (2) summary
      cd00220
      Location:33 → 200
      VMO-I; Vitelline membrane outer layer protein I (VMO-I) domain, VMO-I is one of the proteins found in the outer layer of the vitelline membrane of poultry eggs; VMO-I, lysozyme, and VMO-II are tightly bound to ovomucin; this complex forms the backbone of the ...
      pfam03762
      Location:35 → 199
      VOMI; Vitelline membrane outer layer protein I (VOMI)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55726572..55733432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086320.2 → XP_038942248.1  vitelline membrane outer layer protein 1 homolog isoform X1

      UniProtKB/TrEMBL
      A6HG59
      Conserved Domains (1) summary
      pfam03762
      Location:2 → 136
      VOMI; Vitelline membrane outer layer protein I (VOMI)
    Nucleotide Protein Strain
    Heading Accession and Version

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