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    Tex12 testis expressed 12 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690393, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tex12provided by RGD
    Official Full Name
    testis expressed 12provided by RGD
    Primary source
    RGD:1597300
    See related
    EnsemblRapid:ENSRNOG00000049470 AllianceGenome:RGD:1597300
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in synaptonemal complex assembly. Predicted to act upstream of or within meiotic DNA repair synthesis. Predicted to be located in synaptonemal complex. Predicted to be active in central element. Orthologous to human TEX12 (testis expressed 12). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 62.7), Spleen (RPKM 28.0) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tex12 in Genome Data Viewer
    Location:
    8q23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (59804662..59809595, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (50908161..50913202, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (54991501..54999454, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene 6-pyruvoyl-tetrahydropterin synthase Neighboring gene beta-carotene oxygenase 2 Neighboring gene interleukin 18 Neighboring gene succinate dehydrogenase complex subunit D Neighboring gene translocase of inner mitochondrial membrane 8 homolog B Neighboring gene NKAP domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within meiotic DNA repair synthesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptonemal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within synaptonemal complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in central element IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in central element ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptonemal complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    testis-expressed protein 12
    Names
    testis expressed gene 12
    testis-expressed sequence 12 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191106.2NP_001178035.1  testis-expressed protein 12

      See identical proteins and their annotated locations for NP_001178035.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6J4D8, D4A057
      Related
      ENSRNOP00000013014.4, ENSRNOT00000013014.7
      Conserved Domains (1) summary
      pfam15219
      Location:28122
      TEX12; Testis-expressed 12

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      59804662..59809595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008766338.4XP_008764560.1  testis-expressed protein 12 isoform X1

      See identical proteins and their annotated locations for XP_008764560.1

      UniProtKB/TrEMBL
      A6J4D8, D4A057
      Conserved Domains (1) summary
      pfam15219
      Location:28122
      TEX12; Testis-expressed 12