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    MLS malate synthase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831690, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MLS
    Official Full Name
    malate synthase
    Primary source
    TAIR:AT5G03860
    Locus tag
    AT5G03860
    See related
    Araport:AT5G03860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    malate synthase; MED24.5
    Summary
    Encodes a protein with malate synthase activity.
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    Genomic context

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    See MLS in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (1032099..1034973, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene Glutaredoxin family protein Neighboring gene Thioredoxin family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lipid utilization, gluconeogenesis, and seedling growth in Arabidopsis mutants lacking the glyoxylate cycle enzyme malate synthase. Cornah JE, et al. J Biol Chem, 2004 Oct 8. PMID 15272001
    2. Identification and molecular properties of SUMO-binding proteins in Arabidopsis. Park HC, et al. Mol Cells, 2011 Aug. PMID 21607647, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203290.1
    NM_120467.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables malate synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glyoxylate cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    malate synthase
    NP_001190219.1
    • malate synthase (MLS); FUNCTIONS IN: malate synthase activity; INVOLVED IN: glyoxylate cycle; CONTAINS InterPro DOMAIN/s: Malate synthase-like (InterPro:IPR011076), Malate synthase, conserved site (InterPro:IPR019830), Malate synthase A (InterPro:IPR006252), Malate synthase (InterPro:IPR001465).
    NP_196006.1
    • malate synthase (MLS); FUNCTIONS IN: malate synthase activity; INVOLVED IN: glyoxylate cycle; EXPRESSED IN: seed, leaf; CONTAINS InterPro DOMAIN/s: Malate synthase-like (InterPro:IPR011076), Malate synthase, conserved site (InterPro:IPR019830), Malate synthase A (InterPro:IPR006252), Malate synthase (InterPro:IPR001465); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1032099..1034973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120467.4 → NP_196006.1  malate synthase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196006.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LZC3
      UniProtKB/TrEMBL
      A0A178UKL7, A0A5S9Y203
      Conserved Domains (1) summary
      PLN02626
      Location:10 → 562
      PLN02626; malate synthase

    2. NM_001203290.1 → NP_001190219.1  malate synthase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190219.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LZC3
      UniProtKB/TrEMBL
      A0A178UKL7, A0A5S9Y203
      Conserved Domains (1) summary
      PLN02626
      Location:10 → 562
      PLN02626; malate synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZC3.1

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