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    Tubd1 tubulin, delta 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287592, updated on 27-Dec-2024

    Summary

    Official Symbol
    Tubd1provided by RGD
    Official Full Name
    tubulin, delta 1provided by RGD
    Primary source
    RGD:1311967
    See related
    EnsemblRapid:ENSRNOG00000053309 AllianceGenome:RGD:1311967
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization; mitotic cell cycle; and positive regulation of smoothened signaling pathway. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm and microtubule. Orthologous to human TUBD1 (tubulin delta 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 56.7), Thymus (RPKM 54.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tubd1 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (71865446..71888731)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (71367936..71391387)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (73865828..73886976)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene ring finger protein, transmembrane 1 Neighboring gene ribosomal protein S6 kinase B1 Neighboring gene microRNA 21 Neighboring gene vacuole membrane protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of smoothened signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105826.3NP_001099296.1  tubulin delta chain

      See identical proteins and their annotated locations for NP_001099296.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A0G2K6I6, A0A8I6G7A6, A6HHR1
      Related
      ENSRNOP00000082344.1, ENSRNOT00000094153.2
      Conserved Domains (1) summary
      cd02189
      Location:2482
      delta_zeta_tubulin-like; The delta- and zeta-tubulin families

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      71865446..71888731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085560.2XP_038941488.1  tubulin delta chain isoform X6

      UniProtKB/TrEMBL
      A0A0G2K6I6, A0A8I6G7A6, A6HHR1
      Conserved Domains (1) summary
      cd02189
      Location:2482
      delta_zeta_tubulin-like; The delta- and zeta-tubulin families
    2. XM_063268691.1XP_063124761.1  tubulin delta chain isoform X2

    3. XM_063268692.1XP_063124762.1  tubulin delta chain isoform X4

    4. XM_039085552.2XP_038941480.1  tubulin delta chain isoform X1

      UniProtKB/TrEMBL
      A0A0G2K6I6, A6HHR2
      Related
      ENSRNOP00000080626.2, ENSRNOT00000094778.2
      Conserved Domains (1) summary
      cd02189
      Location:2452
      delta_zeta_tubulin-like; The delta- and zeta-tubulin families
    5. XM_039085551.2XP_038941479.1  tubulin delta chain isoform X1

      UniProtKB/TrEMBL
      A0A0G2K6I6, A6HHR2
      Related
      ENSRNOP00000073829.2, ENSRNOT00000081012.3
      Conserved Domains (1) summary
      cd02189
      Location:2452
      delta_zeta_tubulin-like; The delta- and zeta-tubulin families
    6. XM_039085553.2XP_038941481.1  tubulin delta chain isoform X1

      UniProtKB/TrEMBL
      A0A0G2K6I6, A6HHR2
      Conserved Domains (1) summary
      cd02189
      Location:2452
      delta_zeta_tubulin-like; The delta- and zeta-tubulin families
    7. XM_039085556.2XP_038941484.1  tubulin delta chain isoform X3

      Conserved Domains (1) summary
      cd02189
      Location:1333
      delta_zeta_tubulin-like; The delta- and zeta-tubulin families
    8. XM_039085558.2XP_038941486.1  tubulin delta chain isoform X5

      Conserved Domains (1) summary
      cd02189
      Location:8261
      delta_zeta_tubulin-like; The delta- and zeta-tubulin families