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    Rrp9 ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363134, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rrp9provided by RGD
    Official Full Name
    ribosomal RNA processing 9, U3 small nucleolar RNA binding proteinprovided by RGD
    Primary source
    RGD:1307881
    See related
    EnsemblRapid:ENSRNOG00000012927 AllianceGenome:RGD:1307881
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rnu3ip2
    Summary
    Predicted to enable snoRNA binding activity. Predicted to contribute to U3 snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of box C/D methylation guide snoRNP complex and small-subunit processome. Orthologous to human RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 77.0), Spleen (RPKM 65.6) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rrp9 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (115995119..116004832)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (107116411..107126123)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (115179899..115188551)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 14b Neighboring gene poly(rC) binding protein 4 Neighboring gene G protein-coupled receptor 62 Neighboring gene poly (ADP-ribose) polymerase family, member 3 Neighboring gene IQ motif containing F1 Neighboring gene IQ motif containing F5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to U3 snoRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables U3 snoRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of box C/D methylation guide snoRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    U3 small nucleolar RNA-interacting protein 2
    Names
    RNA, U3 small nucleolar interacting protein 2
    RRP9, small subunit (SSU) processome component, homolog
    ribosomal RNA processing 9, small subunit (SSU) processome component, homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108778.1NP_001102248.1  U3 small nucleolar RNA-interacting protein 2

      See identical proteins and their annotated locations for NP_001102248.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473954
      UniProtKB/TrEMBL
      A0A8I6GFG9, B0BND5, F7EPW8
      Related
      ENSRNOP00000017469.5, ENSRNOT00000017469.8
      Conserved Domains (2) summary
      cd00200
      Location:142442
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:152200
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      115995119..116004832
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081786.2XP_038937714.1  U3 small nucleolar RNA-interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GFG9, B0BND5, F7EPW8
      Conserved Domains (2) summary
      cd00200
      Location:142442
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:152200
      7WD40; WD40 repeat [structural motif]
    2. XM_063265820.1XP_063121890.1  U3 small nucleolar RNA-interacting protein 2 isoform X2

    RNA

    1. XR_005487871.2 RNA Sequence