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    Plasma-membrane choline transporter family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820777, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Plasma-membrane choline transporter family protein
    Primary source
    TAIR:AT3G15380
    Locus tag
    AT3G15380
    See related
    Araport:AT3G15380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtCTL1; CHER1; choline transporter-like 1
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    10
    Sequence:
    Chromosome: 3; NC_003074.8 (5193203..5196591)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene thioredoxin M-type 4 Neighboring gene expansin 12 Neighboring gene silencing defective 5 Neighboring gene HrpN-interacting protein from malus protein Neighboring gene anther 20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Choline transporter-like 1 (CTL1) positively regulates apical hook development in etiolated Arabidopsis seedlings. Cai G, et al. Biochem Biophys Res Commun, 2020 Apr 30. PMID 32111354
    2. A new vesicle trafficking regulator CTL1 plays a crucial role in ion homeostasis. Gao YQ, et al. PLoS Biol, 2017 Dec. PMID 29284002, Free PMC Article
    3. Arabidopsis choline transporter-like 1 (CTL1) regulates secretory trafficking of auxin transporters to control seedling growth. Wang Y, et al. PLoS Biol, 2017 Dec. PMID 29283991, Free PMC Article
    4. Choline transporter-like1 (CHER1) is crucial for plasmodesmata maturation in Arabidopsis thaliana. Kraner ME, et al. Plant J, 2017 Jan. PMID 27743414
    5. CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication. Dettmer J, et al. Nat Commun, 2014 Jul 10. PMID 25008948

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Choline transporter-like 1 (CTL1) positively regulates apical hook development in etiolated Arabidopsis seedlings.
      Title: Choline transporter-like 1 (CTL1) positively regulates apical hook development in etiolated Arabidopsis seedlings.
    2. CTL1 is involved in regulating vesicle trafficking and is thus required for the trafficking of proteins essential for ion transport and plasmodesmata development.
      Title: A new vesicle trafficking regulator CTL1 plays a crucial role in ion homeostasis.
    3. CTL1 controls seedling growth and apical hook development by regulating intracellular trafficking of PIN-type auxin transporters.
      Title: Arabidopsis choline transporter-like 1 (CTL1) regulates secretory trafficking of auxin transporters to control seedling growth.
    4. CHER1 is crucial for plasmodesmata maturation in Arabidopsis thaliana.
      Title: Choline transporter-like1 (CHER1) is crucial for plasmodesmata maturation in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    NM_112406.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables choline transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within choline transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in choline transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lipid homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in monoatomic ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phloem development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plasmodesma organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in plasmodesma organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in plasmodesmata-mediated intercellular transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in procambium histogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sieve element differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within xylem and phloem pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with early endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in early endosome membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in phragmoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 
    located_in secondary plasmodesma IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in sieve plate IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in symplast IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in trans-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Plasma-membrane choline transporter family protein
    NP_566511.1
    • Plasma-membrane choline transporter family protein; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF580 (InterPro:IPR007603); Has 948 Blast hits to 937 proteins in 182 species: Archae - 0; Bacteria - 0; Metazoa - 503; Fungi - 120; Plants - 118; Viruses - 0; Other Eukaryotes - 207 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5193203..5196591
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112406.5 → NP_566511.1  Plasma-membrane choline transporter family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566511.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94AN2, Q9LUQ4, Q9M7X1
      UniProtKB/TrEMBL
      A0A178VKI5, A0A5S9XCQ8, A0A654F7F7
      Conserved Domains (1) summary
      pfam04515
      Location:326 → 670
      Choline_transpo; Plasma-membrane choline transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94AN2.1

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