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    CFM2 CRM family member 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821288, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CFM2
    Official Full Name
    CRM family member 2
    Primary source
    TAIR:AT3G01370
    Locus tag
    AT3G01370
    See related
    Araport:AT3G01370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana CRM family member 2; ATCFM2; CRM family member 2; T13O15.1; T13O15_1
    Summary
    Encodes a protein containing a CRM domain that is involved in group I and group II intron splicing.
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    Genomic context

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    See CFM2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Sequence:
    Chromosome: 3; NC_003074.8 (139011..143782)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily protein Neighboring gene plant viral-response family protein (DUF716) Neighboring gene ncRNA Neighboring gene sulfatase and phosphatidylinositolglycan class N domain-containing protein Neighboring gene vacuolar membrane ATPase 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The pentatricopeptide repeat protein EMB1270 interacts with CFM2 to splice specific group II introns in Arabidopsis chloroplasts. Zhang L, et al. J Integr Plant Biol, 2021 Nov. PMID 34427970
    2. A CRM domain protein functions dually in group I and group II intron splicing in land plant chloroplasts. Asakura Y, et al. Plant Cell, 2007 Dec. PMID 18065687, Free PMC Article
    3. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The pentatricopeptide repeat protein EMB1270 interacts with CFM2 to splice specific group II introns in Arabidopsis chloroplasts.
      Title: The pentatricopeptide repeat protein EMB1270 interacts with CFM2 to splice specific group II introns in Arabidopsis chloroplasts.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111003.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within Group I intron splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within Group II intron splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in plastid stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CRM family member 2
    NP_186786.2
    • CRM family member 2 (CFM2); FUNCTIONS IN: RNA binding; INVOLVED IN: Group I intron splicing, Group II intron splicing; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA-binding, CRM domain (InterPro:IPR001890); BEST Arabidopsis thaliana protein match is: CRM family member 3B (TAIR:AT4G14510.1); Has 1269 Blast hits to 881 proteins in 154 species: Archae - 0; Bacteria - 46; Metazoa - 247; Fungi - 72; Plants - 683; Viruses - 4; Other Eukaryotes - 217 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      139011..143782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111003.5 → NP_186786.2  CRM family member 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186786.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L7C2, Q9SGI0
      UniProtKB/TrEMBL
      A0A178VGM9, A0A5S9X873, A0A654F342
      Conserved Domains (2) summary
      smart01103
      Location:579 → 666
      CRS1_YhbY; Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly
      pfam01985
      Location:169 → 249
      CRS1_YhbY; CRS1 / YhbY (CRM) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L7C2.1

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