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    CDC45 cell division cycle 45 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822101, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDC45
    Official Full Name
    cell division cycle 45
    Primary source
    TAIR:AT3G25100
    Locus tag
    AT3G25100
    See related
    Araport:AT3G25100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cell division cycle 45
    Summary
    Required for normal meiosis, may act in the last round of DNA replication prior to meiosis, sequence similar to yeast CDC45
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    Genomic context

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    See CDC45 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (9143916..9146236)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene fatA acyl-ACP thioesterase Neighboring gene Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A CDC45 homolog in Arabidopsis is essential for meiosis, as shown by RNA interference-induced gene silencing. Stevens R, et al. Plant Cell, 2004 Jan. PMID 14660803, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_113414.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gametophyte development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within premeiotic DNA replication IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cell division cycle 45
    NP_189146.1
    • cell division cycle 45 (CDC45); CONTAINS InterPro DOMAIN/s: CDC45-like protein (InterPro:IPR003874); Has 1810 Blast hits to 1657 proteins in 252 species: Archae - 0; Bacteria - 25; Metazoa - 666; Fungi - 449; Plants - 176; Viruses - 35; Other Eukaryotes - 459 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9143916..9146236
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113414.3 → NP_189146.1  cell division cycle 45 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189146.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VCG0, A0A5S9XFP9, A0A654FFV2, A0A7G2ESJ2, Q9LSG6
      Conserved Domains (1) summary
      pfam02724
      Location:28 → 595
      CDC45; CDC45-like protein
    Nucleotide Protein
    Heading Accession and Version

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